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- Title
Antianemic activity of polymetallocomplexes of pectin polysaccharides with Fe<sup>2+</sup>, Co<sup>2+</sup>, and Cu<sup>2+</sup> with different ratios of d metals.
- Authors
Vyshtakalyuk, A. B.; Karaseva, A. N.; Karlin, V. V.; Minzanova, S. T.; Mironov, V. F.; Konovalov, A. I.
- Abstract
The antianemic activity of water-soluble polymetallocomplexes of pectin polysaccharides containing d metal ions — Fe2+, Co2+, and Cu2+ — at different ratios was studied in laboratory rats. The results showed that complexes had marked stimulatory effects on hematopoietic processes, with increases in hemoglobin concentrations and erythrocyte counts, along with intensification of the recovery of hematological parameters after anemia induced by hemorrhage. The highest level of activity on hematological measures was obtained with the polymetallocomplex containing Fe2+, Co2+, and Cu2+ ions at a ratio close to 1:1:1.
- Subjects
ANEMIA treatment; POLYSACCHARIDES; PECTINS; HEMOGLOBIN polymorphisms; LABORATORY rats; HEMATOLOGICAL oncology
- Publication
Pharmaceutical Chemistry Journal, 2008, Vol 42, Issue 6, p309
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-008-0130-x