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- Title
Les sphéroïdes et les organoïdes d'oviducte: de nouveaux modèles pour mieux comprendre la fertilité.
- Authors
Reynaud, Karine; Mahé, Coline; Schmaltz, Lorraine; Mermillod, Pascal; Saint-Dizier, Marie
- Abstract
Spheroids and organoids are cellular models capable of selforganisation in 3 dimensions in vitro and which mimic the organisation of an organ. The oviduct, located between the ovary and the uterus, is the site of final gamete maturation, fertilisation and early embryonic development. Our objective is to develop oviduct spheroids and organoids to better understand the roles of this organ in the mechanisms of sperm storage and selection by the maternal organism, as well as in the embryo-maternal dialogue during the development of the young embryo.
- Subjects
EMBRYOLOGY; OVIDUCT; GAMETES; OVARIES; UTERUS
- Publication
Médecine de la Reproduction, 2022, Vol 24, Issue 2, p120
- ISSN
2650-8427
- Publication type
Article
- DOI
10.1684/mte.2022.0894