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- Title
Does the Anionic Surfactant Isopropylamine Dodecylbenzene Sulfonate Induce Hepatic Oxidative Stress and Impairment in Carassius auratus gibelio?
- Authors
Zhang, Jianghui; Luo, Yiping; Chen, Xin; Wu, Guangjie; Yuan, Lunqiang
- Abstract
Isopropylamine dodecylbenzene sulfonate (IDS) is a new kind of anionic surfactant (ANS). To preliminarily evaluate the aquatic toxicity of IDS, this study took gibel carp (Carassius auratus gibelio) as the research object. The well-acclimatized fish were divided into six groups and exposed to 0 mg/L, 0.5 mg/L, 1.0 mg/L, 2.0 mg/L, 4.0 mg/L, or 8.0 mg/L of IDS for 7, 14, 21 or 28 days. Our results showed that the superoxide dismutase (SOD) activity and malondialdehyde (MDA) content of the liver were unaffected by IDS exposure, while glutathione peroxidase (GSH-Px) activity was significantly inhibited. Hepatic tissue exhibited pathological damage, characterized by nuclear migration and dissolution and cell boundary blurring. The results suggest that IDS does not cause oxidative stress in the liver, but cause hepatic histopathological damage. GSH-Px can be considered as a biomarker of IDS exposure in gibel carp.
- Subjects
GOLDFISH; ISOPROPYLAMINE; OXIDATIVE stress; GLUTATHIONE peroxidase; SUPEROXIDE dismutase; ANIONIC surfactants
- Publication
Bulletin of Environmental Contamination & Toxicology, 2021, Vol 107, Issue 3, p487
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-021-03248-x