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- Title
Factores epidemiológicos en la inmunopatogénesis de la alergia a los alimentos.
- Authors
Álvarez, Juan R. Urrego; Bonfante, Luz del C. Hernández; Cano, Javier Marrugo
- Abstract
Food allergy (FA) is an important health problem in developed countries. In these countries the prevalence ranging between 6 to 8% in children and about 3% in adults. A recent metaanalysis showed a marked heterogeneity in the prevalence of food allergy that could be a result of differences in study design, methodology, or differences between populations. In addition, there are very few studies to reveal the true dimension of the problem in developing countries. In these countries the few existing studies were conducted with questionnaires and without confirmation of the diagnoses with objective test. In general the symptoms of food allergy occurs more frequently in the early stages of life and are almost always triggered by a limited number of food, such as milk, eggs, peanuts, etc. Recently, several animal models have been developed and they have facilitated the understanding of some of the immunopathogenic mechanisms involved in this disease. In various epidemiological and experimental studies have suggested that some genetic and environmental factors (Nutritional, microbial, pharmacological and pollutants) could play an important role in the epidemiology and the pathogenesis of FA.
- Subjects
FOOD allergy; ALLERGIES; IMMUNOPATHOLOGY; DEVELOPED countries; META-analysis; ANIMAL models in research; MILK; EGGS; PEANUTS
- Publication
Salud Uninorte, 2009, Vol 25, Issue 2, p258
- ISSN
0120-5552
- Publication type
Article