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- Title
Essential Fatty Acids as Biomedicines in Cardiac Health.
- Authors
Balta, Igori; Stef, Lavinia; Pet, Ioan; Iancu, Tiberiu; Stef, Ducu; Corcionivoschi, Nicolae
- Abstract
The destructive impact of cardiovascular diseases on health, including heart failure, peripheral artery disease, atherosclerosis, stroke, and other cardiac pathological conditions, positions these health conditions as leading causes of increased global mortality rates, thereby impacting the human quality of life. The considerable changes in modern lifestyles, including the increase in food intake and the change in eating habits, will unavoidably lead to an unbalanced consumption of essential fatty acids, with a direct effect on cardiovascular health problems. In the last decade, essential fatty acids have become the main focus of scientific research in medical fields aiming to establish their impact for preventing cardiovascular diseases and the associated risk factors. Specifically, polyunsaturated fatty acids (PUFA), such as omega 3 fatty acids, and monounsaturated fatty acids from various sources are mentioned in the literature as having a cardio-protective role, due to various biological mechanisms that are still to be clarified. This review aims to describe the major biological mechanisms of how diets rich in essential fatty acids, or simply essential fatty acid administration, could have anti-inflammatory, vasodilatory, anti-arrhythmic, antithrombotic, antioxidant, and anti-atherogenic effects. This review describes findings originating from clinical studies in which dietary sources of FAs were tested for their role in mitigating the impact of heart disorders in human health.
- Subjects
ESSENTIAL fatty acids; MONOUNSATURATED fatty acids; CARDIOVASCULAR diseases; PERIPHERAL vascular diseases; UNSATURATED fatty acids; CARDIOVASCULAR diseases risk factors; HEART failure
- Publication
Biomedicines, 2021, Vol 9, Issue 10, p1466
- ISSN
2227-9059
- Publication type
Article
- DOI
10.3390/biomedicines9101466