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A Dual-Administration Microtracer Technique to Characterize the Absorption, Distribution, Metabolism, and Excretion of [<sup>14</sup>C]Seletalisib (UCB5857) in Healthy Subjects.
- Published in:
- Journal of Clinical Pharmacology, 2017, v. 57, n. 12, p. 1582, doi. 10.1002/jcph.954
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- Publication type:
- Article
Clinical Bridging Studies and Modeling Approach for Implementation of a Patient Centric Sampling Technique in Padsevonil Clinical Development.
- Published in:
- AAPS Journal, 2024, v. 26, n. 1, p. 1, doi. 10.1208/s12248-023-00866-7
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- Article
Stability and compatibility study of cefepime in comparison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory treatment of cystic fibrosis patients and to administration in intensive care units.
- Published in:
- 2003
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- Publication type:
- journal article
Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.
- Published in:
- Pharmaceutical Research, 2020, v. 37, n. 9, p. N.PAG, doi. 10.1007/s11095-020-02867-z
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- Article
Role of the OATP Transporter Family and a Benzbromarone-SensitiveEfflux Transporter in the Hepatocellular Disposition of Vincristine.
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- Pharmaceutical Research, 2017, v. 34, n. 11, p. 2336, doi. 10.1007/s11095-017-2241-0
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- Publication type:
- Article
Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 4, p. 770, doi. 10.1002/cpt.2503
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- Article
N-Alkylprotoporphyrin Formation and Hepatic Porphyria in Dogs After Administration of a New Antiepileptic Drug Candidate: Mechanism and Species Specificity.
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- Toxicological Sciences, 2014, v. 141, n. 2, p. 353, doi. 10.1093/toxsci/kfu131
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- Publication type:
- Article
Use of a physiologically based pharmacokinetic–pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial.
- Published in:
- British Journal of Clinical Pharmacology, 2021, v. 87, n. 3, p. 1378, doi. 10.1111/bcp.14528
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- Article
Pharmacokinetics of Staccato<sup>®</sup> alprazolam in healthy adult participants in two phase 1 studies: An open‐label smoker study and a randomized, placebo‐controlled ethnobridging study.
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- Epilepsia (Series 4), 2024, v. 65, n. 4, p. 887, doi. 10.1111/epi.17901
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- Publication type:
- Article
Brivaracetam, a selective high-affinity synaptic vesicle protein 2A ( SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action.
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- Epilepsia (Series 4), 2016, v. 57, n. 2, p. 201, doi. 10.1111/epi.13267
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- Publication type:
- Article
Potential role for human P-glycoprotein in the transport of lacosamide.
- Published in:
- Epilepsia (Series 4), 2013, v. 54, n. 7, p. 1154, doi. 10.1111/epi.12158
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- Publication type:
- Article
Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.
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- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 3, p. 209, doi. 10.1002/bdd.2052
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- Publication type:
- Article