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- Title
Immunoglobulin Superfamily Virus Receptors and the Evolution of Adaptive Immunity.
- Authors
Dermody, Terence S.; Kirchner, Eva; Guglielmi, Kristen M.; Stehle, Thilo
- Abstract
In this article the authors discuss the receptors of the immunoglobulin superfamily and the development of adaptive immunity. They state that restricted intracellular pathogens depend on the molecules of the cell surface to attach and enter into the host cells. Also investigated is the interaction of the pathogen-host during a prolonged period of evolutionary struggle that may have led to the growth of antigen-specific immune responses in vertebrates.
- Subjects
IMMUNOGLOBULINS; IMMUNITY; INTRACELLULAR pathogens; CELL membranes; ANTIGENS; VERTEBRATES
- Publication
PLoS Pathogens, 2009, Vol 5, Issue 11, p1
- ISSN
1553-7366
- Publication type
Opinion
- DOI
10.1371/journal.ppat.1000481