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- Title
Daptomycin efficacy in the central nervous system of a patient with disseminated methicillin-resistant Staphylococcus aureus infection: a case report.
- Authors
Taglietti, Fabrizio; Campanile, Floriana; Capone, Alessandro; Di Caro, Antonino; Grilli, Elisabetta; Stazi, Giulia; Bertuccio, Taschia; Petrosillo, Nicola; Stefani, Stefania
- Abstract
<bold>Introduction: </bold>Staphylococcus aureus has emerged as a major nosocomial pathogen in the last decades and also represents the second most common pathogen isolated from patients in outpatient settings. Although methicillin-resistant S.aureus infections were traditionally limited to hospitals, community-associated cases of methicillin-resistant S.aureus infections have been reported. In our case, we observed an unexpected event during treatment.<bold>Case Presentation: </bold>A 60-year-old Caucasian man developed fever and multiple muscle and brain abscesses caused by Panton-Valentine leukocidin-negative community-associated methicillin-resistant S. aureus.<bold>Conclusion: </bold>Although our patient was given antimicrobials active against the isolated methicillin-resistant S. aureus strain, it was only after the introduction of daptomycin that his skin, soft tissue and muscle lesions and also brain manifestations improved.
- Subjects
STAPHYLOCOCCUS aureus infections; METHICILLIN resistance; DRUG resistance in microorganisms; MICROCOCCACEAE
- Publication
Journal of Medical Case Reports, 2012, Vol 6, Issue 1, p264
- ISSN
1752-1947
- Publication type
journal article
- DOI
10.1186/1752-1947-6-264