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- Title
Addition–cyclization reactions of furan-2-carbonyl isothiocyanate with nitrogen nucleophiles as a synthetic route to novel azines and azoles of potential biological activity.
- Authors
Abdel Hamid, Atef M.
- Abstract
Heterocyclization of furan-2-carbonyl isothiocyanate 1 with a variety of aliphatic and aromatic nitrogen nucleophiles resulted in the formation of a new series of heterocycles including triazines, pyrimidines, oxadiazines, imidazolidines, thiadiazoles and their condensed candidates. The antibacterial screening for a group of the newly synthesized compounds showed that they possess moderate antibacterial activities against examples of Gram-positive and Gram-negative bacteria.
- Subjects
THIADIAZOLES; AZINES; AZOLES; TRIAZINES; IMIDAZOLIDINES; GRAM-positive bacteria
- Publication
Journal of the Iranian Chemical Society, 2019, Vol 16, Issue 9, p1853
- ISSN
1735-207X
- Publication type
Article
- DOI
10.1007/s13738-019-01659-6