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- Title
Characterization of antigenic α-Gal-containing extracellular vesicles (EVs) from Trypanosoma cruzi.
- Authors
Karimi, Nasim Hosseini; Mendes, Maria Tays; Portillo, Susana; Grajeda, Brian; Ellis, Cameron; Almeida, Igor C.
- Abstract
The article discusses a study characterization of antigenic alfa-Gal-containing extracellular vesicles (EVs) from Trypanosoma cruzi. It reports tha Highly immunogenic alfa-Gal-containing epitopes found on trypomastigote GPI-anchored mucins (tGPI-mucins or TcMUC II) are strongly recognized by patients with Chagas disease (CD). It mentions alfa-Gal glycotopes have been used as BMKs for follow-up of chemotherapy in children and lately in adults with CD, and as prophylactic vaccine targets.
- Subjects
TRYPANOSOMA cruzi; CHAGAS' disease treatment; TRYPANOSOMIASIS; CANCER chemotherapy
- Publication
Revista Médica de Panamá, 2020, Vol 40, p99
- ISSN
0379-1629
- Publication type
Article