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- Title
Pseudo-hypoaldosteronism secondary to infantile urinary tract infections: role of ultrasound.
- Authors
Graziano, Noemi; Agostoni, Carlo; Chiaraviglio, Francesca; Betti, Céline; Piffer, Arianna; Bianchetti, Mario G.; Milani, Gregorio P.
- Abstract
Background: The biochemical hallmarks of transient pseudo-hypoaldosteronism associated with a pyelonephritis include hyponatremia, hyperkalemia, and acidosis. We tested if the kidney-urinary tract ultrasound helps in predicting the diagnosis of overt pseudo-hypoaldosteronism in infants with a pyelonephritis. Cases presentation: Between 2013 and 2020, we managed 71 previously healthy infants 4 weeks to 24 months of age with a pyelonephritis (42 males and 29 females) and made the biochemical diagnosis of pseudo-hypoaldosteronism in 17 (24%). Infants with and without pseudo-hypoaldosteronism did not significantly differ with respect to the prevalence of kidney-urinary tract ultrasound abnormalities, graded by means of the UTD classification system of urinary tract abnormalities. Conclusions: Kidney-urinary tract ultrasound is almost routinely obtained in children with a febrile urinary tract infection. Our experience does not support the hypothesis that ultrasound might be relevant for the diagnosis of overt transient pseudo-hypoaldosteronism in babies affected by a urinary tract infection. Our data confirm the assumption that negative studies may be important for advancing clinical practice.
- Subjects
PYELONEPHRITIS; CONFIDENCE intervals; URINARY tract infections; URINARY organs; HYPONATREMIA; DESCRIPTIVE statistics; ODDS ratio; HYPOALDOSTERONISM; ACIDOSIS; CHILDREN
- Publication
Italian Journal of Pediatrics, 2022, Vol 48, Issue 1, p1
- ISSN
1720-8424
- Publication type
Article
- DOI
10.1186/s13052-022-01203-y