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The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination.
- Published in:
- Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.748033
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- Article
DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation.
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- Nature Communications, 2023, p. 1, doi. 10.1038/s41467-023-36211-x
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- Article
Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies.
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- Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13045-020-00924-z
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- Article
Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells.
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- Nature Medicine, 2000, v. 6, n. 6, p. 652, doi. 10.1038/76225
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- Article
Clinical and Pathological Comparison of Young Adult Women with Hepatocellular Carcinoma with and without Exposure to Oral Contraceptives.
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- American Journal of Gastroenterology (Springer Nature), 1985, v. 80, n. 6, p. 479
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- Article
Co-targeting BCL-X<sub>L</sub> and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice.
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- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-022-01296-8
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- Article
Metnase promotes restart and repair of stalled and collapsed replication forks.
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- Nucleic Acids Research, 2010, v. 38, n. 17, p. 5681, doi. 10.1093/nar/gkq339
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- Article
The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation.
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- Nucleic Acids Research, 2008, v. 36, n. 18, p. 5822, doi. 10.1093/nar/gkn560
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- Article
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27210-x
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- Article
The Role of PCNA Posttranslational Modifications in Translesion Synthesis.
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- Journal of Nucleic Acids, 2010, p. 1, doi. 10.4061/2010/761217
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- Article
Oct-4 Is Critical for Survival/Antiapoptosis of Murine Embryonic Stem Cells Subjected to Stress: Effects Associated with Stat3/Survivin.
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- Stem Cells, 2008, v. 26, n. 1, p. 30, doi. 10.1634/stemcells.2007-0401
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- Article
Mechanisms of oncogenic chromosomal translocations.
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- Annals of the New York Academy of Sciences, 2014, v. 1310, n. 1, p. 89, doi. 10.1111/nyas.12370
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- Article
Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46922-4
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- Article
More forks on the road to replication stress recovery.
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- Journal of Molecular Cell Biology, 2011, v. 3, n. 1, p. 4, doi. 10.1093/jmcb/mjq049
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- Article
The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5’ End of SS-Overhang Cleavage.
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- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139418
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- Article
NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells.
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- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0123808
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- Article
Metnase Mediates Resistance to Topoisomerase II Inhibitors in Breast Cancer Cells.
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- PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005323
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- Article
Effects of CC, CXC, C, and CX<sub>3</sub>C Chemokines on Proliferation of Myeloid Progenitor Cells, and Insights into SDF-1-Induced Chemotaxis of Progenitors<sup>a</sup>.
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- Annals of the New York Academy of Sciences, 1999, v. 872, n. 1, p. 142, doi. 10.1111/j.1749-6632.1999.tb08460.x
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- Article
RNA binding to human METTL3-METTL14 restricts N<sup>6</sup>-deoxyadenosine methylation of DNA in vitro.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.67150
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- Article
DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10408-5
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- Article
The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
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- 2017
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- Publication type:
- journal article
A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease.
- Published in:
- PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0252805
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- Article
Tandem high dose chemotherapy with autologous bone marrow transplantation for initial relapse of testicular germ cell cancer.
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- 1997
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- Publication type:
- journal article
Neoamphimedine Circumvents Metnase-Enhanced DNA Topoisomerase IIα Activity Through ATP-Competitive Inhibition.
- Published in:
- Marine Drugs, 2011, v. 9, n. 11, p. 2397, doi. 10.3390/md9112397
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- Article
Cytotoxic activity of the titanium alkoxide (OPy)Ti(4AP) against cancer colony forming cells.
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- Investigational New Drugs, 2012, v. 30, n. 1, p. 114, doi. 10.1007/s10637-010-9530-3
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- Article
Metnase and EEPD1: DNA Repair Functions and Potential Targets in Cancer Therapy.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.808757
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- Publication type:
- Article
The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control.
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- Oncogene, 1999, v. 18, n. 50, p. 7091, doi. 10.1038/sj.onc.1203201
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- Article
PREVENTING THE CHROMOSOMAL TRANSLOCATIONS THAT CAUSE CANCER.
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- Transactions of the American Clinical & Climatological Association, 2016, v. 127, p. 176
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- Publication type:
- Article
Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development.
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- Immunology, 2002, v. 107, n. 4, p. 444, doi. 10.1046/j.1365-2567.2002.01523.x
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- Article
Resistance to the BCL-XL degrader DT2216 in T-cell acute lymphoblastic leukemia is rare and correlates with decreased BCL-XL proteolysis.
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- Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 1, p. 89, doi. 10.1007/s00280-022-04490-8
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- Publication type:
- Article
Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition.
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- 2017
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- Publication type:
- journal article
The chemokine CCL21 protects normal marrow progenitors from Ara-C cytotoxicity.
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- Cancer Chemotherapy & Pharmacology, 2002, v. 50, n. 2, p. 163, doi. 10.1007/s00280-002-0486-7
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- Article
EEPD1 promotes repair of oxidatively-stressed replication forks.
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- NAR Cancer, 2023, v. 5, n. 4, p. 1, doi. 10.1093/narcan/zcac044
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- Publication type:
- Article
EEPD1 promotes repair of oxidatively-stressed replication forks.
- Published in:
- NAR Cancer, 2023, v. 5, n. 1, p. 1, doi. 10.1093/narcan/zcac044
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- Publication type:
- Article
Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection.
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- PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0147230
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- Publication type:
- Article
The RNA Demethylase ALKBH5 Maintains Endoplasmic Reticulum Homeostasis by Regulating UPR, Autophagy, and Mitochondrial Function.
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- Cells (2073-4409), 2023, v. 12, n. 9, p. 1283, doi. 10.3390/cells12091283
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- Publication type:
- Article
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.
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- Nucleic Acids Research, 2023, v. 52, n. 22, p. 12224, doi. 10.1093/nar/gkad952
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- Article
The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04716-5
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- Article
Metnase/SETMAR: a domesticated primate transposase that enhances DNA repair, replication, and decatenation.
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- Genetica, 2010, v. 138, n. 5, p. 559, doi. 10.1007/s10709-010-9452-1
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- Article
Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors.
- Published in:
- Molecules, 2021, v. 26, n. 4, p. 983, doi. 10.3390/molecules26040983
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- Article
Two Cycles of High Dose Chemotherapy with Autologous Bone Marrow Support for Patients with Locally Advanced Breast Cancer.
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- Breast Journal, 1995, v. 1, n. 5, p. 308, doi. 10.1111/j.1524-4741.1995.tb00254.x
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- Article
Facing the NIH Funding Crisis.
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- JAMA: Journal of the American Medical Association, 2012, v. 308, n. 22, p. 2343, doi. 10.1001/jama.2012.45067
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- Article
Cellular Responses to Widespread DNA Replication Stress.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16903, doi. 10.3390/ijms242316903
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- Article
Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing.
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- BMC Molecular Biology, 2014, v. 15, p. 1, doi. 10.1186/1471-2199-15-6
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- Publication type:
- Article
Drugging the Cancers Addicted to DNA Repair.
- Published in:
- 2017
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- Publication type:
- journal article
Repressing DNA Repair to Enhance Chemotherapy: Targeting MyD88 in Colon Cancer.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 13, p. 926, doi. 10.1093/jnci/djt148
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- Publication type:
- Article
Structural basis of RNA cap modification by SARS-CoV-2.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17496-8
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- Publication type:
- Article
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16903-4
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- Publication type:
- Article