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- Title
Precipitating Factors for Hospitalization with Heart Failure: Prevalence and Clinical Impact Observations from the Gulf CARE (Gulf aCute heArt failuRe rEgistry).
- Authors
Salam, Amar M.; Sulaiman, Kadhim; Alsheikh-Ali, Alawi A.; Singh, Rajvir; AlHabib, Khalid F.; Al-Zakwani, Ibrahim; Asaad, Nidal; Al-Qahtani, Awad; Al-Jarallah, Mohammed; AlMahmeed, Wael; Bulbanat, Bassam; Ridha, Mustafa; Bazargani, Nooshin; Amin, Haitham; Al-Motarreb, Ahmed; Panduranga, Prashanth; AlFaleh, Husam; Shehab, Abdulla; Al Suwaidi, Jassim; Salam, Amar M
- Abstract
<bold>Objective: </bold>Despite the expanding burden of heart failure (HF) worldwide, data on HF precipitating factors (PFs) in developing countries, particularly the Middle East, are very limited. We examined PFs in patients hospitalized with acute HF in a prospective multicenter HF registry from 7 countries in the Middle East.<bold>Method: </bold>Data were derived from the Gulf CARE (Gulf aCute heArt failuRe rEgistry) for a prospective, multinational, multicenter study of consecutive patients hospitalized with HF in 47 hospitals in 7 Middle Eastern countries between February 2012 and November 2012. PFs were determined by the treating physician from a predefined list at the time of hospitalization.<bold>Results: </bold>The study included 5,005 patients hospitalized with acute HF, 2,276 of whom (45.5%) were hospitalized with acute new-onset HF (NOHF) and 2,729 of whom (54.5%) had acute decompensated chronic HF (DCHF). PFs were identified in 4,319 patients (86.3%). The most common PF in the NOHF group was acute coronary syndromes (ACS) (39.2%). In the DCHF group, it was noncompliance with medications (27.8%). Overall, noncompliance with medications was associated with a lower inhospital mortality (OR 0.47; 95% CI 0.28-0.80; p = 0.005) but a higher 1-year mortality (OR 1.43; 95% CI 1.1-1.85; p = 0.007). ACS was associated with higher inhospital mortality (OR 1.84; 95% CI 1.26-2.68; p = 0.002) and higher 1-year mortality (OR 1.62; 95% CI 1.27-2.06; p = 0.001).<bold>Conclusion: </bold>Preventive and therapeutic interventions specifically directed at noncompliance with medications and ACS are warranted in our region.
- Subjects
MIDDLE East; HEART failure; HOSPITAL mortality; PATIENT compliance; ACUTE coronary syndrome; BAYS; RESEARCH; RESEARCH methodology; ACQUISITION of data; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; HOSPITAL care; DRUGS; DEVELOPING countries; LONGITUDINAL method; CARDIOTONIC agents; COMORBIDITY
- Publication
Medical Principles & Practice, 2020, Vol 29, Issue 3, p270
- ISSN
1011-7571
- Publication type
journal article
- DOI
10.1159/000503334