We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
BMI and risk of all-cause mortality in normotensive and hypertensive adults: the rural Chinese cohort study.
- Authors
Zhou, Qionggui; Liu, Xuejiao; Zhao, Yang; Qin, Pei; Ren, Yongcheng; Liu, Dechen; Liu, Leilei; Chen, Xu; Liu, Feiyan; Cheng, Cheng; Guo, Chunmei; Li, Quanman; Tian, Gang; Wu, Xiaoyan; Qie, Ranran; Han, Minghui; Huang, Shengbing; Xu, Lidan; Zhang, Ming; Hu, Dongsheng
- Abstract
<bold>Objective: </bold>The impact of baseline hypertension status on the BMI-mortality association is still unclear. We aimed to examine the moderation effect of hypertension on the BMI-mortality association using a rural Chinese cohort.<bold>Design: </bold>In this cohort study, we investigated the incident of mortality according to different BMI categories by hypertension status.<bold>Setting: </bold>Longitudinal population-based cohort.<bold>Participants: </bold>17 262 adults ≥18 years were recruited from July to August of 2013 and July to August of 2014 from a rural area in China.<bold>Results: </bold>During a median 6-year follow-up, we recorded 1109 deaths (610 with and 499 without hypertension). In adjusted models, as compared with BMI 22-24 kg/m2, with BMI ≤ 18, 18-20, 20-22, 24-26, 26-28, 28-30 and >30 kg/m2, the hazard ratios for mortality in normotensive participants were 1·92 (95% CI 1·23, 3·00), 1·44 (95% CI 1·01, 2·05), 1·14 (95% CI 0·82, 1·58), 0·96 (95% CI 0·70, 1·31), 0·96 (95% CI 0·65, 1·43), 1·32 (95% CI 0·81, 2·14) and 1·32 (95% CI 0·74, 2·35), respectively, and in hypertensive participants were 1·85 (95% CI 1·08, 3·17), 1·67 (95% CI 1·17, 2·39), 1·29 (95% CI 0·95, 1·75), 1·20 (95% CI 0·91, 1·58), 1·10 (95% CI 0·83, 1·46), 1·10 (95% CI 0·80, 1·52) and 0·61 (95% CI 0·40, 0·94), respectively. The risk of mortality was lower in individuals with hypertension with overweight or obesity v. normal weight, especially in older hypertensives (≥60 years old). Sensitivity analyses gave consistent results for both normotensive and hypertensive participants.<bold>Conclusions: </bold>Low BMI was significantly associated with increased risk of all-cause mortality regardless of hypertension status in rural Chinese adults, but high BMI decreased the mortality risk among individuals with hypertension, especially in older hypertensives.
- Subjects
CHINA; MORTALITY; ADULTS; COHORT analysis; HYPERTENSION; HYPERTENSION epidemiology; BODY mass index; LONGITUDINAL method
- Publication
Public Health Nutrition, 2021, Vol 24, Issue 17, p5805
- ISSN
1368-9800
- Publication type
journal article
- DOI
10.1017/S1368980021001592