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- Title
The Number of Harvested LNs Is an Independent Prognostic Factor in Lymph Node Metastasis-negative Patients Who Received Curative Esophagectomy.
- Authors
TORU AOYAMA; YOSUKE ATSUMI; SHINNOSUKE KAWAHARA; HIROSHI TAMAGAWA; AYAKO TAMAGAWA; YUKIO MAEZAWA; KAZUKI KANO; MASAAKI MURAKAWA; KEISUKE KAZAMA; MASAKATSU NUMATA; TAKASHI OSHIMA; NORIO YUKAWA; MUNETAKA MASUDA; YASUSHI RINO
- Abstract
Background/Aim: The aim of the present study was to evaluate the optimal number of harvested LNs (LNs) in patients who were LN metastasis-negative after curative esophagectomy for esophageal cancer. Patients and Methods: Sixty-one patients who underwent curative surgery for esophageal cancer between 2005 and 2017 and diagnosed as lymph node metastasis-negative were included in this study. Results: The 5-year overall survival rates were 27.8% for 0-20 harvested LNs, 35.7% for 21-30 harvested LNs, 79.4% for 31-40 harvested LNs, and 85.2% for ≥41 harvested LNs. Thirty harvested LNs was regarded as the optimal critical point of classification, considering the 5year OS rate. The number of harvested LNs was selected as a significant prognostic factor in both univariate and multivariate analyses. The respective 3-and 5-year OS rates were 50.3% and 36.7% for <30 harvested LNs and 82.4% and 82.4% for ≥30 harvested LNs (p=0.003). Conclusion: Thirty or more harvested LNs was a significant prognostic factor in patients with metastasis-negative LNs after curative esophagectomy for esophageal cancer. Therefore, the number of harvested LNs might be useful for predicting the LN metastasis status in esophageal cancer.
- Subjects
ESOPHAGECTOMY; LYMPH node cancer; CANCER relapse; LYMPHADENECTOMY; SQUAMOUS cell carcinoma
- Publication
In Vivo, 2020, Vol 34, Issue 4, p2021
- ISSN
0258-851X
- Publication type
Article
- DOI
10.21873/invivo.12001