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Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance.
Published in:
EMBO Reports, 2018, v. 19, n. 3, p. 1, doi. 10.15252/embr.201745009
By:
- Bhaskaran, Shylesh;
- Pharaoh, Gavin;
- Ranjit, Rojina;
- Murphy, Ashley;
- Matsuzaki, Satoshi;
- Nair, Binoj C.;
- Forbes, Brittany;
- Gispert, Suzana;
- Auburger, Georg;
- Humphries, Kenneth M.;
- Kinter, Michael;
- Griffin, Timothy M.;
- Deepa, Sathyaseelan S.
Publication type:
Article
Intracellular iron accumulation facilitates mycobacterial infection in old mouse macrophages.
Published in:
GeroScience, 2024, v. 46, n. 2, p. 2739, doi. 10.1007/s11357-023-01048-1
By:
- Kotey, Stephen K.;
- Tan, Xuejuan;
- Fleming, Owen;
- Kasiraju, Ramakrishnama Raju;
- Dagnell, Audrey L.;
- Van Pelt, Kyle N.;
- Rogers, Janet;
- Hartson, Steven D.;
- Thadathil, Nidheesh;
- Selvarani, Ramasamy;
- Ranjit, Rojina;
- Logan, Sreemathi;
- Deepa, Sathyaseelan S.;
- Richardson, Arlan;
- Cheng, Yong
Publication type:
Article
Characterization of novel mouse models to study the role of necroptosis in aging and age-related diseases.
Published in:
GeroScience, 2023, v. 45, n. 6, p. 3241, doi. 10.1007/s11357-023-00955-7
By:
- Selvarani, Ramasamy;
- Van Michelle Nguyen, Hoang;
- Thadathil, Nidheesh;
- Wolf, Roman F.;
- Freeman, Willard M.;
- Wiley, Christopher D.;
- Deepa, Sathyaseelan S.;
- Richardson, Arlan
Publication type:
Article
Necroptosis increases with age in the brain and contributes to age-related neuroinflammation.
Published in:
GeroScience, 2021, v. 43, n. 5, p. 2345, doi. 10.1007/s11357-021-00448-5
By:
- Thadathil, Nidheesh;
- Nicklas, Evan H.;
- Mohammed, Sabira;
- Lewis Jr, Tommy L.;
- Richardson, Arlan;
- Deepa, Sathyaseelan S.
Publication type:
Article
The potential role of necroptosis in inflammaging and aging.
Published in:
GeroScience, 2019, v. 41, n. 6, p. 795, doi. 10.1007/s11357-019-00131-w
By:
- Royce, Gordon H.;
- Brown-Borg, Holly M.;
- Deepa, Sathyaseelan S.
Publication type:
Article
Accelerated decline in cognition in a mouse model of increased oxidative stress.
Published in:
GeroScience, 2019, v. 41, n. 5, p. 591, doi. 10.1007/s11357-019-00105-y
By:
- Logan, Sreemathi;
- Royce, Gordon H.;
- Owen, Daniel;
- Farley, Julie;
- Ranjo-Bishop, Michelle;
- Sonntag, William E.;
- Deepa, Sathyaseelan S.
Publication type:
Article
The effect of different levels of dietary restriction on glucose homeostasis and metabolic memory.
Published in:
GeroScience, 2018, v. 40, n. 2, p. 139, doi. 10.1007/s11357-018-0011-5
By:
- Matyi, Stephanie;
- Jackson, Jordan;
- Garrett, Karla;
- Deepa, Sathyaseelan S.;
- Unnikrishnan, Archana
Publication type:
Article
The Geropathology Grading Platform demonstrates that mice null for Cu/Zn-superoxide dismutase show accelerated biological aging.
Published in:
GeroScience, 2018, v. 40, n. 2, p. 97, doi. 10.1007/s11357-018-0008-0
By:
- Snider, Timothy A.;
- Richardson, Arlan;
- Stoner, Julie A.;
- Deepa, Sathyaseelan S.
Publication type:
Article
Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 10, p. 1605, doi. 10.1038/jcbfm.2013.116
By:
- Lin, Ai-Ling;
- Pulliam, Daniel A;
- Deepa, Sathyaseelan S;
- Halloran, Jonathan J;
- Hussong, Stacy A;
- Burbank, Raquel R;
- Bresnen, Andrew;
- Liu, Yuhong;
- Podlutskaya, Natalia;
- Soundararajan, Anuradha;
- Muir, Eric;
- Duong, Timothy Q;
- Bokov, Alex F;
- Viscomi, Carlo;
- Zeviani, Massimo;
- Richardson, Arlan G;
- Van Remmen, Holly;
- Fox, Peter T;
- Galvan, Veronica
Publication type:
Article
Complex IV-deficient Surf1<sup>-/-</sup> mice initiate mitochondrial stress responses.
Published in:
Biochemical Journal, 2014, v. 462, n. 2, p. 359, doi. 10.1042/BJ20140291
By:
- PULLIAM, Daniel A.;
- DEEPA, Sathyaseelan S.;
- Yuhong LIU;
- HILL, Shauna;
- Ai-Ling LIN;
- BHATTACHARYA, Arunabh;
- Yun SHI;
- SLOANE, Lauren;
- VISCOMI, Carlo;
- ZEVIANI, Massimo;
- VAN REMMEN, Holly
Publication type:
Article
Senolytic treatment reduces cell senescence and necroptosis in Sod1 knockout mice that is associated with reduced inflammation and hepatocellular carcinoma.
Published in:
Aging Cell, 2022, v. 21, n. 8, p. 1, doi. 10.1111/acel.13676
By:
- Thadathil, Nidheesh;
- Selvarani, Ramasamy;
- Mohammed, Sabira;
- Nicklas, Evan H.;
- Tran, Albert L.;
- Kamal, Maria;
- Luo, Wenyi;
- Brown, Jacob L.;
- Lawrence, Marcus M.;
- Borowik, Agnieszka K.;
- Miller, Benjamin F.;
- Van Remmen, Holly;
- Richardson, Arlan;
- Deepa, Sathyaseelan S.
Publication type:
Article
Necroptosis contributes to chronic inflammation and fibrosis in aging liver.
Published in:
Aging Cell, 2021, v. 20, n. 12, p. 1, doi. 10.1111/acel.13512
By:
- Mohammed, Sabira;
- Thadathil, Nidheesh;
- Selvarani, Ramasamy;
- Nicklas, Evan H.;
- Wang, Dawei;
- Miller, Benjamin F.;
- Richardson, Arlan;
- Deepa, Sathyaseelan S.
Publication type:
Article
Improved insulin sensitivity associated with reduced mitochondrial complex IV assembly and activity.
Published in:
FASEB Journal, 2013, v. 27, n. 4, p. 1371, doi. 10.1096/fj.12-221879
By:
- Deepa, Sathyaseelan S.;
- Pulliam, Daniel;
- Hill, Shauna;
- Yun Shi;
- Walsh, Michael E.;
- Salmon, Adam;
- Sloane, Lauren;
- Ning Zhang;
- Zeviani, Massimo;
- Viscomi, Carlo;
- Musi, Nicolas;
- Van Remmen, Holly
Publication type:
Article
Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences with bioactivities.
Published in:
Glycobiology, 2013, v. 23, n. 2, p. 155, doi. 10.1093/glycob/cws137
By:
- Mizumoto, Shuji;
- Murakoshi, Saori;
- Kalayanamitra, Kittiwan;
- Deepa, Sarama Sathyaseelan;
- Fukui, Shigeyuki;
- Kongtawelert, Prachya;
- Yamada, Shuhei;
- Sugahara, Kazuyuki
Publication type:
Article
Necroptosis increases with age and is reduced by dietary restriction.
Published in:
Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12770
By:
- Deepa, Sathyaseelan S.;
- Unnikrishnan, Archana;
- Matyi, Stephanie;
- Hadad, Niran;
- Richardson, Arlan
Publication type:
Article
Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice.
Published in:
Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12769
By:
- Deepa, Sathyaseelan S.;
- Pharaoh, Gavin;
- Kinter, Michael;
- Diaz, Vivian;
- Fok, Wilson C.;
- Riddle, Kaitlyn;
- Pulliam, Daniel;
- Hill, Shauna;
- Fischer, Kathleen E.;
- Soto, Vanessa;
- Georgescu, Constantin;
- Wren, Jonathan D.;
- Viscomi, Carlo;
- Richardson, Arlan;
- Van Remmen, Holly
Publication type:
Article
Animals lacking link protein have attenuated perineuronal nets and persistent plasticity.
Published in:
Brain: A Journal of Neurology, 2010, v. 133, n. 8, p. 2331, doi. 10.1093/brain/awq145
By:
- Carulli, Daniela;
- Pizzorusso, Tommaso;
- Kwok, Jessica C. F.;
- Putignano, Elena;
- Poli, Andrea;
- Forostyak, Serhiy;
- Andrews, Melissa R.;
- Deepa, Sathyaseelan S.;
- Glant, Tibor T.;
- Fawcett, James W.
Publication type:
Article
Phosphorylation-Dependent Nuclear-Cytoplasmic Translocation of LKB1: A Molecular Mechanism for Adiponectin- and Metformin-Stimulated AMPK Activation.
Published in:
Diabetes, 2007, v. 56, p. A13
By:
- Sathyaseelan, Deepa;
- Xuming Mao;
- Changhua Wang;
- Riojas, Ramon A.;
- Mapes, Rebekka;
- Feng Liu;
- Dong, Lily Q.
Publication type:
Article
Augmented Efficacy of Uttroside B over Sorafenib in a Murine Model of Human Hepatocellular Carcinoma.
Published in:
Pharmaceuticals (14248247), 2022, v. 15, n. 5, p. 636, doi. 10.3390/ph15050636
By:
- Swetha, Mundanattu;
- Keerthana, Chenicheri K.;
- Rayginia, Tennyson P.;
- Nath, Lekshmi R.;
- Haritha, Nair Hariprasad;
- Shabna, Anwar;
- Kalimuthu, Kalishwaralal;
- Thangarasu, Arun K.;
- Aiswarya, Sreekumar U.;
- Jannet, Somaraj;
- Pillai, Sreekumar;
- Harikumar, Kuzhuvelil B.;
- Sundaram, Sankar;
- Anto, Nikhil Ponnoor;
- Wu, Dee H.;
- Lankalapalli, Ravi S.;
- Towner, Rheal;
- Isakov, Noah;
- Deepa, Sathyaseelan S.;
- Anto, Ruby John
Publication type:
Article
Non-Necroptotic Roles of MLKL in Diet-Induced Obesity, Liver Pathology, and Insulin Sensitivity: Insights from a High-Fat, High-Fructose, High-Cholesterol Diet Mouse Model.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2813, doi. 10.3390/ijms25052813
By:
- Ohene-Marfo, Phoebe;
- Nguyen, Hoang Van M.;
- Mohammed, Sabira;
- Thadathil, Nidheesh;
- Tran, Albert;
- Nicklas, Evan H.;
- Wang, Dawei;
- Selvarani, Ramasamy;
- Farriester, Jacob W.;
- Varshney, Rohan;
- Kinter, Michael;
- Richardson, Arlan;
- Rudolph, Michael C.;
- Deepa, Sathyaseelan S.
Publication type:
Article

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