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- Title
Reconsidering strategies for poor responder patients. What do we know now? What is reasonable to expect from the future?
- Authors
Surcel, Mihai; Neamţiu, Iulia; Nemeti, Georgiana; Surcel, Alina; Goidescu, Iulian; Mureşan, Daniel; Axente, Dan D.
- Abstract
The strategy for the poor responder patients continues to represent one of the most challenging tasks for the clinicians. The reduced number of follicles reaching advanced stages of folliculogenesis may be due to atresia/cellular mitosis malfunction in the early stages of follicle development (exclusively controlled by paracrine factors) or to endocrine activity issues (especially of gonadotropins) in the final stages of development. Due to its complexity, the reproductive process inevitably entails a wide variety of possible pathologies. The aim of the present study was to review the currently available data on poor responder patients and to anticipate further steps for a better management of this condition.
- Subjects
OVARIAN atresia; OVARY abnormalities; FOLLICLE-stimulating hormone; MITOSIS; KARYOKINESIS
- Publication
Obstetrică şi Ginecologie, 2021, Vol 69, Issue 1, p44
- ISSN
1220-5532
- Publication type
Article
- DOI
10.26416/obsgin.69.1.2021.4821