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Model-Predicted Impact of ECG Monitoring Strategies During Bedaquiline Treatment.
Published in:
Open Forum Infectious Diseases, 2022, v. 9, n. 8, p. 1, doi. 10.1093/ofid/ofac372
By:
- Beek, Stijn W van;
- Tanneau, Lénaïg;
- Meintjes, Graeme;
- Wasserman, Sean;
- Gandhi, Neel R;
- Campbell, Angie;
- Viljoen, Charle A;
- Wiesner, Lubbe;
- Aarnoutse, Rob E;
- Maartens, Gary;
- Brust, James C M;
- Svensson, Elin M
Publication type:
Article
Combined quantitative tuberculosis biomarker model for time-to-positivity and colony forming unit to support tuberculosis drug development.
Published in:
Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1067295
By:
- Alsoud, Rami Ayoun;
- Svensson, Robin J.;
- Svensson, Elin M.;
- Gillespie, Stephen H.;
- Boeree, Martin J.;
- Diacon, Andreas H.;
- Dawson, Rodney;
- Aarnoutse, Rob E.;
- Simonsson, Ulrika S. H.
Publication type:
Article
Editorial: Pharmacometrics--tools to assure optimal medicine use in low- and middle-income countries.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 01, doi. 10.3389/fphar.2022.1034807
By:
- Abulfathi, Ahmed A.;
- Chaba, Linda A.;
- Svensson, Elin M.;
- Pillai, Goonaseelan C.;
- Rosenkranz, Bernd
Publication type:
Article
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin.
Published in:
Pharmaceutics, 2022, v. 14, n. 8, p. 1530, doi. 10.3390/pharmaceutics14081530
By:
- Keutzer, Lina;
- You, Huifang;
- Farnoud, Ali;
- Nyberg, Joakim;
- Wicha, Sebastian G.;
- Maher-Edwards, Gareth;
- Vlasakakis, Georgios;
- Moghaddam, Gita Khalili;
- Svensson, Elin M.;
- Menden, Michael P.;
- Simonsson, Ulrika S. H.
Publication type:
Article
Physiologically-Based Pharmacokinetic Modelling to Predict the Pharmacokinetics and Pharmacodynamics of Linezolid in Adults and Children with Tuberculous Meningitis.
Published in:
Antibiotics (2079-6382), 2023, v. 12, n. 4, p. 702, doi. 10.3390/antibiotics12040702
By:
- Litjens, Carlijn H. C.;
- Verscheijden, Laurens F. M.;
- Svensson, Elin M.;
- van den Broek, Petra H. H.;
- van Hove, Hedwig;
- Koenderink, Jan B.;
- Russel, Frans G. M.;
- Aarnoutse, Rob E.;
- te Brake, Lindsey H. M.
Publication type:
Article
The Population Pharmacokinetics of Meropenem in Adult Patients With Rifampicin-Sensitive Pulmonary Tuberculosis.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.637618
By:
- Abulfathi, Ahmed A.;
- de Jager, Veronique;
- van Brakel, Elana;
- Reuter, Helmuth;
- Gupte, Nikhil;
- Vanker, Naadira;
- Barnes, Grace L.;
- Nuermberger, Eric;
- Dorman, Susan E.;
- Diacon, Andreas H.;
- Dooley, Kelly E.;
- Svensson, Elin M.
Publication type:
Article
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
Published in:
2022
By:
- De Jager, Veronique;
- Gupte, Nikhil;
- Nunes, Silvia;
- Barnes, Grace L;
- van Wijk, Rob Christiaan;
- Mostert, Joni;
- Dorman, Susan E;
- Abulfathi, Ahmed A;
- Upton, Caryn M;
- Faraj, Alan;
- Nuermberger, Eric L;
- Lamichhane, Gyanu;
- Svensson, Elin M;
- Simonsson, Ulrika S H;
- Diacon, Andreas H;
- Dooley, Kelly E
Publication type:
journal article
Constructing a representative in‐silico population for paediatric simulations: Application to HIV‐positive African children.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 7, p. 2847, doi. 10.1111/bcp.14694
By:
- Wasmann, Roeland E.;
- Svensson, Elin M.;
- Walker, A. Sarah;
- Clements, Michelle N.;
- Denti, Paolo
Publication type:
Article
The pharmacokinetics of para‐aminosalicylic acid and its relationship to efficacy and intolerance.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 11, p. 2123, doi. 10.1111/bcp.14395
By:
- Abulfathi, Ahmed A.;
- Donald, Peter R.;
- Adams, Kim;
- Svensson, Elin M.;
- Diacon, Andreas H.;
- Reuter, Helmuth
Publication type:
Article
Understanding the drug exposure–response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug‐resistant tuberculosis.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 5, p. 913, doi. 10.1111/bcp.14199
By:
- Tanneau, Lénaïg;
- Karlsson, Mats O.;
- Svensson, Elin M.
Publication type:
Article
Relative bioavailability of bedaquiline tablets suspended in water: Implications for dosing in children.
Published in:
British Journal of Clinical Pharmacology, 2018, v. 84, n. 10, p. 2384, doi. 10.1111/bcp.13696
By:
- Svensson, Elin M.;
- du Bois, Jeannine;
- Kitshoff, Rene;
- de Jager, Veronique R.;
- Wiesner, Lubbe;
- Norman, Jennifer;
- Nachman, Sharon;
- Smith, Betsy;
- Diacon, Andreas H.;
- Hesseling, Anneke C.;
- Garcia‐Prats, Anthony J.
Publication type:
Article
Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies.
Published in:
European Journal of Clinical Pharmacology, 2021, v. 77, n. 5, p. 727, doi. 10.1007/s00228-020-03042-4
By:
- Wasmann, Roeland E.;
- Svensson, Elin M.;
- Schalkwijk, Stein J.;
- Brüggemann, Roger J.;
- ter Heine, Rob
Publication type:
Article
Probability of mycobactericidal activity of para-aminosalicylic acid with novel dosing regimens.
Published in:
European Journal of Clinical Pharmacology, 2020, v. 76, n. 11, p. 1557, doi. 10.1007/s00228-020-02943-8
By:
- Abulfathi, Ahmed A.;
- Assawasuwannakit, Piyanan;
- Donald, Peter R.;
- Diacon, Andreas H.;
- Reuter, Helmuth;
- Svensson, Elin M.
Publication type:
Article
Optimizing Dosing and Fixed-Dose Combinations of Rifampicin, Isoniazid, and Pyrazinamide in Pediatric Patients With Tuberculosis: A Prospective Population Pharmacokinetic Study.
Published in:
Clinical Infectious Diseases, 2022, v. 75, n. 1, p. 141, doi. 10.1093/cid/ciab908
By:
- Denti, Paolo;
- Wasmann, Roeland E;
- Rie, Annelies van;
- Winckler, Jana;
- Bekker, Adrie;
- Rabie, Helena;
- Hesseling, Anneke C;
- Laan, Louvina E van der;
- Gonzalez-Martinez, Carmen;
- Zar, Heather J;
- Davies, Gerry;
- Wiesner, Lubbe;
- Svensson, Elin M;
- McIlleron, Helen M
Publication type:
Article
High-Dose Oral and Intravenous Rifampicin for the Treatment of Tuberculous Meningitis in Predominantly Human Immunodeficiency Virus (HIV)-Positive Ugandan Adults: A Phase II Open-Label Randomized Controlled Trial.
Published in:
Clinical Infectious Diseases, 2021, v. 73, n. 5, p. 876, doi. 10.1093/cid/ciab162
By:
- Cresswell, Fiona V;
- Meya, David B;
- Kagimu, Enock;
- Grint, Daniel;
- Brake, Lindsey te;
- Kasibante, John;
- Martyn, Emily;
- Rutakingirwa, Morris;
- Quinn, Carson M;
- Okirwoth, Micheal;
- Tugume, Lillian;
- Ssembambulidde, Kenneth;
- Musubire, Abdu K;
- Bangdiwala, Ananta S;
- Buzibye, Allan;
- Muzoora, Conrad;
- Svensson, Elin M;
- Aarnoutse, Rob;
- Boulware, David R;
- Elliott, Alison M
Publication type:
Article
Rifampicin Can Be Given as Flat-Dosing Instead of Weight-Band Dosing.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 12, p. 3055, doi. 10.1093/cid/ciz1202
By:
- Susanto, Budi O;
- Svensson, Robin J;
- Svensson, Elin M;
- Aarnoutse, Rob;
- Boeree, Martin J;
- Simonsson, Ulrika S H
Publication type:
Article
Model-Based Meta-analysis of Rifampicin Exposure and Mortality in Indonesian Tuberculous Meningitis Trials.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 8, p. 1817, doi. 10.1093/cid/ciz1071
By:
- Svensson, Elin M;
- Dian, Sofiati;
- Brake, Lindsey Te;
- Ganiem, Ahmad Rizal;
- Yunivita, Vycke;
- Laarhoven, Arjan van;
- Crevel, Reinout Van;
- Ruslami, Rovina;
- Aarnoutse, Rob E
Publication type:
Article
The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.
Published in:
Clinical Infectious Diseases, 2018, v. 67, n. 1, p. 34, doi. 10.1093/cid/ciy026
By:
- Svensson, Elin M;
- Svensson, Robin J;
- Brake, Lindsey H M te;
- Boeree, Martin J;
- Heinrich, Norbert;
- Konsten, Sarah;
- Churchyard, Gavin;
- Dawson, Rodney;
- Diacon, Andreas H;
- Kibiki, Gibson S
Publication type:
Article
Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 4, p. 873, doi. 10.1002/cpt.2685
By:
- Tanneau, Lénaïg;
- Karlsson, Mats O.;
- Rosenkranz, Susan L.;
- Cramer, Yoninah S.;
- Shenje, Justin;
- Upton, Caryn M.;
- Morganroth, Joel;
- Diacon, Andreas H.;
- Maartens, Gary;
- Dooley, Kelly E.;
- Svensson, Elin M.
Publication type:
Article
Power to identify exposure‐response relationships in phase IIa pulmonary tuberculosis trials with multi‐dimensional bacterial load modeling.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 3, p. 374, doi. 10.1002/psp4.13089
By:
- Koele, Simon E.;
- Dorlo, Thomas P. C.;
- Upton, Caryn M.;
- Aarnoutse, Rob E.;
- Svensson, Elin M.
Publication type:
Article
Optimizing the design of a pharmacokinetic trial to evaluate the dosing scheme of a novel tuberculosis drug in children living with or without HIV.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 2, p. 270, doi. 10.1002/psp4.13077
By:
- Montepiedra, Grace;
- Svensson, Elin M.;
- Wong, Weng Kee;
- Hooker, Andrew C.
Publication type:
Article
Exposure–safety analysis of QTc interval and transaminase levels following bedaquiline administration in patients with drug‐resistant tuberculosis.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 12, p. 1538, doi. 10.1002/psp4.12722
By:
- Tanneau, Lénaïg;
- Svensson, Elin M.;
- Rossenu, Stefaan;
- Karlsson, Mats O.
Publication type:
Article
Pharmacometrics meets statistics—A synergy for modern drug development.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 10, p. 1134, doi. 10.1002/psp4.12696
By:
- Ryeznik, Yevgen;
- Sverdlov, Oleksandr;
- Svensson, Elin M.;
- Montepiedra, Grace;
- Hooker, Andrew C.;
- Wong, Weng Kee
Publication type:
Article
A population pharmacokinetics analysis assessing the exposure of raltegravir once‐daily 1200 mg in pregnant women living with HIV.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 2, p. 161, doi. 10.1002/psp4.12586
By:
- Bukkems, Vera E.;
- Post, Teun M.;
- Colbers, Angela P.;
- Burger, David M.;
- Svensson, Elin M.
Publication type:
Article
Characterizing Absorption Properties of Dispersible Pretomanid Tablets Using Population Pharmacokinetic Modelling.
Published in:
Clinical Pharmacokinetics, 2022, v. 61, n. 11, p. 1585, doi. 10.1007/s40262-022-01163-w
By:
- Zou, Yuanxi;
- Nedelman, Jerry;
- Lombardi, Antonio;
- Pappas, Frances;
- Karlsson, Mats O.;
- Svensson, Elin M.
Publication type:
Article
Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline.
Published in:
Clinical Pharmacokinetics, 2022, v. 61, n. 8, p. 1177, doi. 10.1007/s40262-022-01133-2
By:
- Tanneau, Lénaïg;
- Karlsson, Mats O.;
- Diacon, Andreas H.;
- Shenje, Justin;
- De Los Rios, Jorge;
- Wiesner, Lubbe;
- Upton, Caryn M.;
- Dooley, Kelly E.;
- Maartens, Gary;
- Svensson, Elin M.
Publication type:
Article
Population Pharmacokinetics and Bayesian Dose Adjustment to Advance TDM of Anti-TB Drugs.
Published in:
Clinical Pharmacokinetics, 2021, v. 60, n. 6, p. 685, doi. 10.1007/s40262-021-00997-0
By:
- Sturkenboom, Marieke G. G.;
- Märtson, Anne-Grete;
- Svensson, Elin M.;
- Sloan, Derek J.;
- Dooley, Kelly E.;
- van den Elsen, Simone H. J.;
- Denti, Paolo;
- Peloquin, Charles A.;
- Aarnoutse, Rob E.;
- Alffenaar, Jan-Willem C.
Publication type:
Article
Correction to: A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis.
Published in:
2021
By:
- van Beek, Stijn W.;
- ter Heine, Rob;
- Alffenaar, Jan-Willem C.;
- Magis-Escurra, Cecile;
- Aarnoutse, Rob E.;
- Svensson, Elin M.;
- the Isoniazid Precision Dosing Group;
- Boeree, M. J.;
- Burhan, E.;
- Dawson, R.;
- Diacon, A. H.;
- Gillespie, S.;
- Mtabho, C. M.;
- Ntingiya, N. E.;
- Heinrich, N.;
- Hoefsloot, W.;
- Hoelscher, M.;
- Kibiki, G.;
- Reither, K.;
- Sanne, I.
Publication type:
Correction Notice
A Model-Informed Method for the Purpose of Precision Dosing of Isoniazid in Pulmonary Tuberculosis.
Published in:
Clinical Pharmacokinetics, 2021, v. 60, n. 7, p. 943, doi. 10.1007/s40262-020-00971-2
By:
- van Beek, Stijn W.;
- ter Heine, Rob;
- Alffenaar, Jan-Willem C.;
- Magis-Escurra, Cecile;
- Aarnoutse, Rob E.;
- Svensson, Elin M.;
- the Isoniazid Precision Dosing Group;
- Boeree, M. J.;
- Burhan, E.;
- Dawson, R.;
- Diacon, A. H.;
- Gillespie, S.;
- Mtabho, C. M.;
- Ntingiya, N. E.;
- Heinrich, N.;
- Hoefsloot, W.;
- Hoelscher, M.;
- Kibiki, G.;
- Reither, K.;
- Sanne, I.
Publication type:
Article
Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis.
Published in:
Clinical Pharmacokinetics, 2021, v. 60, n. 5, p. 649, doi. 10.1007/s40262-020-00972-1
By:
- de Rouw, Nikki;
- Boosman, Rene J.;
- Huitema, Alwin D. R.;
- Hilbrands, Luuk B.;
- Svensson, Elin M.;
- Derijks, Hieronymus J.;
- van den Heuvel, Michel M.;
- Burger, David M.;
- ter Heine, Rob
Publication type:
Article
Correction to: Evidence-Based Design of Fixed-Dose Combinations: Principles and Application to Pediatric Anti-Tuberculosis Therapy.
Published in:
2020
By:
- Svensson, Elin M.;
- Yngman, Gunnar;
- Denti, Paolo;
- McIlleron, Helen;
- Kjellsson, Maria C.;
- Karlsson, Mats O.
Publication type:
corrected article
Clinical Pharmacokinetics and Pharmacodynamics of Rifampicin in Human Tuberculosis.
Published in:
2019
By:
- Abulfathi, Ahmed Aliyu;
- Decloedt, Eric H.;
- Svensson, Elin M.;
- Diacon, Andreas H.;
- Donald, Peter;
- Reuter, Helmuth
Publication type:
journal article
Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin.
Published in:
2019
By:
- van Beek, Stijn W.;
- ter Heine, Rob;
- Keizer, Ron J.;
- Magis-Escurra, Cecile;
- Aarnoutse, Rob E.;
- Svensson, Elin M.
Publication type:
journal article
Evidence-Based Design of Fixed-Dose Combinations: Principles and Application to Pediatric Anti-Tuberculosis Therapy.
Published in:
2018
By:
- Svensson, Elin M.;
- Yngman, Gunnar;
- Denti, Paolo;
- McIlleron, Helen;
- Kjellsson, Maria C.;
- Karlsson, Mats O.
Publication type:
journal article
Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling.
Published in:
Journal of Clinical Pharmacology, 2022, v. 62, n. 3, p. 385, doi. 10.1002/jcph.1972
By:
- Litjens, Carlijn H. C.;
- Verscheijden, Laurens F. M.;
- Bolwerk, Celine;
- Greupink, Rick;
- Koenderink, Jan B.;
- van den Broek, Petra H. H.;
- van den Heuvel, Jeroen J. M. W.;
- Svensson, Elin M.;
- Boeree, Martin J.;
- Magis-Escurra, Cecile;
- Hoefsloot, Wouter;
- van Crevel, Reinout;
- van Laarhoven, Arjan;
- van Ingen, Jakko;
- Kuipers, Saskia;
- Ruslami, Rovina;
- Burger, David M.;
- Russel, Frans G. M.;
- Aarnoutse, Rob E.;
- te Brake, Lindsey H. M.
Publication type:
Article
Model-based assessment of the safety of community interventions with primaquine in sub-Saharan Africa.
Published in:
Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-021-05034-4
By:
- van Beek, Stijn W.;
- Svensson, Elin M.;
- Tiono, Alfred B.;
- Okebe, Joseph;
- D'Alessandro, Umberto;
- Gonçalves, Bronner P.;
- Bousema, Teun;
- Drakeley, Chris;
- ter Heine, Rob
Publication type:
Article
Pharmacogenetics of Between-Individual Variability in Plasma Clearance of Bedaquiline and Clofazimine in South Africa.
Published in:
2022
By:
- Haas, David W;
- Abdelwahab, Mahmoud Tareq;
- Beek, Stijn W van;
- Baker, Paxton;
- Maartens, Gary;
- Bradford, Yuki;
- Ritchie, Marylyn D;
- Wasserman, Sean;
- Meintjes, Graeme;
- Beeri, Karen;
- Gandhi, Neel R;
- Svensson, Elin M;
- Denti, Paolo;
- Brust, James C M;
- van Beek, Stijn W
Publication type:
journal article
Greater Early Bactericidal Activity at Higher Rifampicin Doses Revealed by Modeling and Clinical Trial Simulations.
Published in:
2018
By:
- Svensson, Robin J;
- Svensson, Elin M;
- Aarnoutse, Rob E;
- Diacon, Andreas H;
- Dawson, Rodney;
- Gillespie, Stephen H;
- Moodley, Mischka;
- Boeree, Martin J;
- Simonsson, Ulrika S H
Publication type:
journal article
New and Repurposed Drugs for the Treatment of Active Tuberculosis: An Update for Clinicians.
Published in:
Respiration, 2023, v. 102, n. 2, p. 83, doi. 10.1159/000528274
By:
- Aguilar Diaz, Jessica M;
- Abulfathi, Ahmed A;
- te Brake, Lindsey HM;
- van Ingen, Jakko;
- Kuipers, Saskia;
- Magis-Escurra, Cecile;
- Raaijmakers, Jelmer;
- Svensson, Elin M;
- Boeree, Martin J
Publication type:
Article
Investigating the treatment shortening potential of a combination of bedaquiline, delamanid and moxifloxacin with and without sutezolid, in a murine tuberculosis model with confirmed drug exposures.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 10, p. 2607, doi. 10.1093/jac/dkae266
By:
- Walter, Kerstin;
- Brake, Lindsey H M te;
- Lemm, Ann-Kathrin;
- Hoelscher, Michael;
- Svensson, Elin M;
- Hölscher, Christoph;
- Heinrich, Norbert
Publication type:
Article
A pharmacometric multistate model for predicting long-term treatment outcomes of patients with pulmonary TB.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 10, p. 2561, doi. 10.1093/jac/dkae256
By:
- Lin, Yu-Jou;
- Zou, Yuanxi;
- Karlsson, Mats O;
- Svensson, Elin M
Publication type:
Article
Drug concentration at the site of disease in children with pulmonary tuberculosis.
Published in:
2022
By:
- Lopez-Varela, Elisa;
- Abulfathi, Ahmed A.;
- Strydom, Natasha;
- Goussard, Pierre;
- Wyk, Abraham C. van;
- Demers, Anne Marie;
- Deventer, Anneen Van;
- Garcia-Prats, Anthony J.;
- van der Merwe, Johannes;
- Zimmerman, Matthew;
- Carter, Claire L.;
- Janson, Jacques;
- Morrison, Julie;
- Reuter, Helmuth;
- Decloedt, Eric H.;
- Seddon, James A.;
- Svensson, Elin M.;
- Warren, Rob;
- Savic, Radojka M.;
- Dartois, Véronique
Publication type:
journal article
Pharmacokinetics and safety of high-dose rifampicin in children with TB: the Opti-Rif trial.
Published in:
2021
By:
- Garcia-Prats, Anthony J;
- Svensson, Elin M;
- Winckler, Jana;
- Draper, Heather R;
- Fairlie, Lee;
- Laan, Louvina E van der;
- Masenya, Masebole;
- Schaaf, H Simon;
- Wiesner, Lubbe;
- Norman, Jennifer;
- Aarnoutse, Rob E;
- Karlsson, Mats O;
- Denti, Paolo;
- Hesseling, Anneke C;
- van der Laan, Louvina E
Publication type:
journal article
Pharmacokinetics of antiretroviral and tuberculosis drugs in children with HIV/TB co-infection: a systematic review.
Published in:
2020
By:
- Jacobs, Tom G;
- Svensson, Elin M;
- Musiime, Victor;
- Rojo, Pablo;
- Dooley, Kelly E;
- McIlleron, Helen;
- Aarnoutse, Rob E;
- Burger, David M;
- Turkova, Anna;
- Colbers, Angela;
- Group, the WHO Paediatric Antiretroviral Working;
- WHO Paediatric Antiretroviral Working Group
Publication type:
journal article
Clofazimine pharmacokinetics in patients with TB: dosing implications.
Published in:
2020
By:
- Abdelwahab, Mahmoud Tareq;
- Wasserman, Sean;
- Brust, James C M;
- Gandhi, Neel R;
- Meintjes, Graeme;
- Everitt, Daniel;
- Diacon, Andreas;
- Dawson, Rodney;
- Wiesner, Lubbe;
- Svensson, Elin M;
- Maartens, Gary;
- Denti, Paolo
Publication type:
journal article
Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?
Published in:
2020
By:
- Ruth, Mike Marvin;
- Koeken, Valerie A C M;
- Pennings, Lian J;
- Svensson, Elin M;
- Wertheim, Heiman F L;
- Hoefsloot, Wouter;
- Ingen, Jakko van;
- van Ingen, Jakko
Publication type:
journal article
Protein binding of rifampicin is not saturated when using high-dose rifampicin.
Published in:
2019
By:
- Litjens, Carlijn H C;
- Aarnoutse, Rob E;
- Kolmer, Eleonora W J van Ewijk-Beneken;
- Svensson, Elin M;
- Colbers, Angela;
- Burger, David M;
- Boeree, Martin J;
- Brake, Lindsey H M te;
- van Ewijk-Beneken Kolmer, Eleonora W J;
- Te Brake, Lindsey H M;
- PanACEA-MAMS-TB-01 Team
Publication type:
journal article
Modelling of mycobacterial load reveals bedaquiline's exposure-response relationship in patients with drug-resistant TB.
Published in:
2017
By:
- Svensson, Elin M.;
- Karlsson, Mats O.
Publication type:
journal article
Population pharmacokinetic drug-drug interaction pooled analysis of existing data for rifabutin and HIV PIs.
Published in:
2016
By:
- Hennig, Stefanie;
- Svensson, Elin M.;
- Niebecker, Ronald;
- Fourie, P. Bernard;
- Weiner, Marc H.;
- Bonora, Stefano;
- Peloquin, Charles A.;
- Gallicano, Keith;
- Flexner, Charles;
- Pym, Alex;
- Vis, Peter;
- Olliaro, Piero L.;
- McIlleron, Helen;
- Karlsson, Mats O.
Publication type:
journal article
Rifampicin and rifapentine significantly reduce concentrations of bedaquiline, a new anti-TB drug.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 4, p. 1106, doi. 10.1093/jac/dku504
By:
- Svensson, Elin M.;
- Murray, Stephen;
- Karlsson, Mats O.;
- Dooley, Kelly E.
Publication type:
Article

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