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- Title
Evidence for a sorting endosome in Arabidopsis root cells.
- Authors
Jaillais, Yvon; Fobis-Loisy, Isabelle; Miège, Christine; Gaude, Thierry
- Abstract
In eukaryotic cells, the endocytic and secretory pathways are key players in several physiological processes. These pathways are largely inter-connected in animal and yeast cells through organelles named sorting endosomes. Sorting endosomes are multi-vesicular compartments that redirect proteins towards various destinations, such as the lysosomes or vacuoles for degradation, the trans-Golgi network for retrograde transport and the plasma membrane for recycling. In contrast, cross-talk between the endocytic and secretory pathways has not been clearly established in plants, especially in terms of cargo protein trafficking. Here we show by co-localization analyses that endosomes labelled with the AtSORTING NEXIN1 (AtSNX1) protein overlap with the pre-vacuolar compartment in Arabidopsis root cells. In addition, alteration of the routing functions of AtSNX1 endosomes by drug treatments leads to mis-routing of endocytic and secretory cargo proteins. Based on these results, we propose that the AtSNX1 endosomal compartment represents a sorting endosome in root cells, and that this specialized organelle is conserved throughout eukaryotes.
- Subjects
ARABIDOPSIS; ENDOSOMES; PLANT roots; PLANT cells &; tissues; BOTANY
- Publication
Plant Journal, 2008, Vol 53, Issue 2, p237
- ISSN
0960-7412
- Publication type
Article
- DOI
10.1111/j.1365-313X.2007.03338.x