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- Title
Biomarkers in inflammatory bowel diseases: insight into diagnosis, prognosis and treatment.
- Authors
Norouzinia, Mohsen; Chaleshi, Vahid; Mohammad Alizadeh, Amir Houshang; Reza Zali, Mohammad
- Abstract
Inflammatory bowel disease (IBD) is a chronic disease of unknown etiology which mostly involves the intestine and requires a personalized approach for treatment. IBD represents a heterogeneous group of patients with inherently variable disease courses. Hence, the heterogeneity of patient populations may delay the diagnosis, clinical practice and initiation of appropriate treatment. Use of biomarkers for diagnosis and management of IBD is still necessary. Descriptions of the immunological pathway abnormalities in IBD improve assessment to identify the patient's disease status, and relative risk of progression to complicated disease behaviors, and this information may ultimately influence therapeutic decisions. In this study, we try to explain the role of biomarkers in early diagnosis, estimating prognosis, and target agents for correct managements of IBD's patients. This information might be important to provide insight into emerging panels of multiple IBD biomarkers and highlighting the essential role of personalizes panel for each patient.
- Subjects
INFLAMMATORY bowel disease diagnosis; INFLAMMATORY bowel disease treatment; INTESTINES; BIOMARKERS; CHRONIC diseases; CYTOKINES; IMMUNITY; INFLAMMATORY bowel diseases; INTERLEUKINS; INTESTINAL diseases; MEDICAL care; PATIENTS; POPULATION; PROGNOSIS; DISEASE progression; DISEASE complications; ANATOMY; DISEASE risk factors
- Publication
Gastroenterology & Hepatology from Bed to Bench, 2017, Vol 10, Issue 3, p155
- ISSN
2008-2258
- Publication type
Article