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- Title
Endoscopic Treatment of Cis-T2 Glottic Cancer with a CO<sub>2</sub> Laser: 2-Year Survival Analysis of 36 Cases.
- Authors
Taylor, S. Mark; Rigby, Matthew H.
- Abstract
Objective: To report our 2-year survival outcomes for early glottic carcinoma using microsurgical resection with the CO2 laser. Design: A prospective study. Methods: Outcomes from a cohort of 36 patients with glottic cancer staged Cis-T2 (7 Cis, 17 T1, 12 T2) who underwent endoscopic resection using a CO2 laser between January 2002 and June 2005 were studied. The mean follow-up was 27 months (range 0-54 months). All follow-ups were performed at our multidisciplinary head and neck oncology clinic at Dalhousie University, Halifax, Nova Scotia. Results: Using a Kaplan-Meier survival analysis, the 2-year recurrence-free survival for the cohort was 89%, with a standard error of 6.7%. At the time of the study, no patient had died of laryngeal cancer, one patient had died of other disease, and one patient was lost to follow-up. There had been three recurrences in the cohort, two local recurrences (T1), and one recurrence in a regional lymph node (T2). After salvage, all patients with recurrences were disease free at the time of the study. Of 35 cases with follow-up, 60% had no reported problems with voice on their last visit and 17% reported consistent hoarseness or weakness. Conclusion: These results justify the continued treatment of early glottic carcinoma with CO2 laser microsurgery at our centre.
- Subjects
HALIFAX (N.S.); NOVA Scotia; CANCER endoscopic surgery; GLOTTIS cancer; CARBON dioxide lasers; HEALTH outcome assessment; THERAPEUTICS
- Publication
Journal of Otolaryngology -- Head & Neck Surgery, 2008, Vol 37, Issue 4, p582
- ISSN
0707-7270
- Publication type
Article
- DOI
10.2310/7070.2008.0111