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- Title
The treatment of early breast cancer in women over the age of 70.
- Authors
Ring, A.; Reed, M.; Leonard, R.; Kunkler, I.; Muss, H.; Wildiers, H.; Fallowfield, L.; Jones, A.; Coleman, R.
- Abstract
One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarises the existing evidence surrounding the management of early breast cancer in women aged 70 and over. The use of primary surgery and endocrine therapy, and adjuvant chemotherapy, radiotherapy, endocrine therapy and trastuzumab are discussed. Reference is made to ongoing clinical trials in this area and areas of controversy are highlighted.
- Subjects
GERIATRIC oncology; BREAST cancer treatment; HORMONE therapy; RADIOTHERAPY; TRASTUZUMAB; DRUG therapy
- Publication
British Journal of Cancer, 2011, Vol 105, Issue 2, p189
- ISSN
0007-0920
- Publication type
journal article
- DOI
10.1038/bjc.2011.234