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Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia.
Published in:
Pediatric Anesthesia, 2021, v. 31, n. 5, p. 548, doi. 10.1111/pan.14164
By:
- Arnold, Philip;
- Sanaulla, Syed;
- Hampson, Lisa V.;
- Davis, Annette;
- Tan, Jacinth;
- Cowen, Ruth;
- Kaleem, Musa;
- Williams, Alexandra;
- Wadsworth, Ian;
- Jaki, Thomas;
- Anderson, Brian
Publication type:
Article
Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children.
Published in:
2017
By:
- Hampson, Lisa V.;
- Fisch, Roland;
- Van, Linh M.;
- Jaki, Thomas
Publication type:
journal article
Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection.
Published in:
2016
By:
- Jaki, Thomas;
- Hampson, Lisa V.
Publication type:
journal article
Optimizing the data combination rule for seamless phase II/III clinical trials.
Published in:
2015
By:
- Hampson, Lisa V;
- Jennison, Christopher
Publication type:
journal article
Optimizing the data combination rule for seamless phase II/III clinical trials.
Published in:
Statistics in Medicine, 2015, v. 34, n. 1, p. 39, doi. 10.1002/sim.6316
By:
- Hampson, Lisa V.;
- Jennison, Christopher
Publication type:
Article
Bayesian methods for the design and interpretation of clinical trials in very rare diseases.
Published in:
Statistics in Medicine, 2014, v. 33, n. 24, p. 4186, doi. 10.1002/sim.6225
By:
- Hampson, Lisa V.;
- Whitehead, John;
- Eleftheriou, Despina;
- Brogan, Paul
Publication type:
Article
Incorporating prognostic factors into causal estimators: A comparison of methods for randomised controlled trials with a time-to-event outcome.
Published in:
Statistics in Medicine, 2012, v. 31, n. 26, p. 3073, doi. 10.1002/sim.5411
By:
- Hampson, Lisa V.;
- Metcalfe, Chris
Publication type:
Article
Clinical Drug Development in Epilepsy Revisited: A Proposal for a New Paradigm Streamlined Using Extrapolation.
Published in:
2016
By:
- Wadsworth, Ian;
- Jaki, Thomas;
- Sills, Graeme;
- Appleton, Richard;
- Cross, J.;
- Marson, Anthony;
- Martland, Tim;
- McLellan, Ailsa;
- Smith, Philip;
- Pellock, John;
- Hampson, Lisa;
- Sills, Graeme J;
- Cross, J Helen;
- Marson, Anthony G;
- Smith, Philip E M;
- Pellock, John M;
- Hampson, Lisa V
Publication type:
journal article
Bridging across patient subgroups in phase I oncology trials that incorporate animal data.
Published in:
Statistical Methods in Medical Research, 2021, v. 30, n. 4, p. 1057, doi. 10.1177/0962280220986580
By:
- Zheng, Haiyan;
- Hampson, Lisa V;
- Jaki, Thomas
Publication type:
Article
Exposure-response modelling approaches for determining optimal dosing rules in children.
Published in:
2020
By:
- Wadsworth, Ian;
- Hampson, Lisa V;
- Bornkamp, Björn;
- Jaki, Thomas
Publication type:
journal article
A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials.
Published in:
2020
By:
- Zheng, Haiyan;
- Hampson, Lisa V;
- Wandel, Simon
Publication type:
journal article
A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment.
Published in:
2018
By:
- Hampson, Lisa V.;
- Williamson, Paula R.;
- Wilby, Martin J.;
- Jaki, Thomas
Publication type:
journal article
Extrapolation of efficacy and other data to support the development of new medicines for children: A systematic review of methods.
Published in:
2018
By:
- Wadsworth, Ian;
- Hampson, Lisa V;
- Jaki, Thomas
Publication type:
journal article
Elicitation of Expert Prior Opinion: Application to the MYPAN Trial in Childhood Polyarteritis Nodosa.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0120981
By:
- Hampson, Lisa V.;
- Whitehead, John;
- Eleftheriou, Despina;
- Tudur-Smith, Catrin;
- Jones, Rachel;
- Jayne, David;
- Hickey, Helen;
- Beresford, Michael W.;
- Bracaglia, Claudia;
- Caldas, Afonso;
- Cimaz, Rolando;
- Dehoorne, Joke;
- Dolezalova, Pavla;
- Friswell, Mark;
- Jelusic, Marija;
- Marks, Stephen D.;
- Martin, Neil;
- McMahon, Anne-Marie;
- Peitz, Joachim;
- van Royen-Kerkhof, Annet
Publication type:
Article
A New Comprehensive Approach to Assess the Probability of Success of Development Programs Before Pivotal Trials.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 1050, doi. 10.1002/cpt.2488
By:
- Hampson, Lisa V.;
- Holzhauer, Björn;
- Bornkamp, Björn;
- Kahn, Joseph;
- Lange, Markus R.;
- Luo, Wen‐Lin;
- Singh, Pritibha;
- Ballerstedt, Steffen;
- Cioppa, Giovanni Della
Publication type:
Article
Bridging the gap: a review of dose investigations in paediatric investigation plans.
Published in:
British Journal of Clinical Pharmacology, 2014, v. 78, n. 4, p. 898, doi. 10.1111/bcp.12402
By:
- Hampson, Lisa V.;
- Herold, Ralf;
- Posch, Martin;
- Saperia, Julia;
- Whitehead, Anne
Publication type:
Article
Adaptive designs in clinical trials: why use them, and how to run and report them.
Published in:
2018
By:
- Pallmann, Philip;
- Bedding, Alun W.;
- Choodari-Oskooei, Babak;
- Dimairo, Munyaradzi;
- Flight, Laura;
- Hampson, Lisa V.;
- Holmes, Jane;
- Mander, Adrian P.;
- Odondi, Lang’o;
- Sydes, Matthew R.;
- Villar, Sofía S.;
- Wason, James M. S.;
- Weir, Christopher J.;
- Wheeler, Graham M.;
- Yap, Christina;
- Jaki, Thomas;
- Odondi, Lang'o;
- Villar, Sofía S
Publication type:
journal article
A Bayesian decision‐theoretic approach to incorporate preclinical information into phase I oncology trials.
Published in:
Biometrical Journal, 2020, v. 62, n. 6, p. 1408, doi. 10.1002/bimj.201900161
By:
- Zheng, Haiyan;
- Hampson, Lisa V.
Publication type:
Article
Eliciting judgements about dependent quantities of interest: The SHeffield ELicitation Framework extension and copula methods illustrated using an asthma case study.
Published in:
Pharmaceutical Statistics, 2022, v. 21, n. 5, p. 1005, doi. 10.1002/pst.2212
By:
- Holzhauer, Björn;
- Hampson, Lisa V.;
- Gosling, John Paul;
- Bornkamp, Björn;
- Kahn, Joseph;
- Lange, Markus R.;
- Luo, Wen‐Lin;
- Brindicci, Caterina;
- Lawrence, David;
- Ballerstedt, Steffen;
- O'Hagan, Anthony
Publication type:
Article
Improving the assessment of the probability of success in late stage drug development.
Published in:
Pharmaceutical Statistics, 2022, v. 21, n. 2, p. 439, doi. 10.1002/pst.2179
By:
- Hampson, Lisa V.;
- Bornkamp, Björn;
- Holzhauer, Björn;
- Kahn, Joseph;
- Lange, Markus R.;
- Luo, Wen‐Lin;
- Cioppa, Giovanni Della;
- Stott, Kelvin;
- Ballerstedt, Steffen
Publication type:
Article
Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593‐606, Sep/Oct 2018., DOI:https://doi.org/10.1002/pst.1873
Published in:
Pharmaceutical Statistics, 2019, v. 18, n. 3, p. 284, doi. 10.1002/pst.1942
By:
- Jaki, Thomas;
- Gordon, Allan;
- Forster, Pamela;
- Bijnens, Luc;
- Bornkamp, Bjoern;
- Brannath, Werner;
- Fontana, Roberto;
- Gasparini, Mauro;
- Hampson, Lisa V.;
- Jacobs, Tom;
- Jones, Byron;
- Paoletti, Xavier;
- Posch, Martin;
- Titman, Andrew;
- Vonk, Richardus;
- Koenig, Franz
Publication type:
Article
Assurance methods for designing a clinical trial with a delayed treatment effect.
Published in:
Statistics in Medicine, 2024, v. 43, n. 19, p. 3595, doi. 10.1002/sim.10136
By:
- Salsbury, James A.;
- Oakley, Jeremy E.;
- Julious, Steven A.;
- Hampson, Lisa V.
Publication type:
Article
Correction to: Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA2 guidance.
Published in:
2019
By:
- Sones, William;
- Julious, Steven A.;
- Rothwell, Joanne C.;
- Ramsay, Craig Robert;
- Hampson, Lisa V.;
- Emsley, Richard;
- Walters, Stephen J.;
- Hewitt, Catherine;
- Bland, Martin;
- Fergusson, Dean A.;
- Berlin, Jesse A.;
- Altman, Doug;
- Vale, Luke David;
- Cook, Jonathan Alistair
Publication type:
corrected article
DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.
Published in:
2018
By:
- Cook, Jonathan A;
- Julious, Steven A;
- Sones, William;
- Hampson, Lisa V;
- Hewitt, Catherine;
- Berlin, Jesse A;
- Ashby, Deborah;
- Emsley, Richard;
- Fergusson, Dean A;
- Walters, Stephen J;
- Wilson, Edward C F;
- Maclennan, Graeme;
- Stallard, Nigel;
- Rothwell, Joanne C;
- Bland, Martin;
- Brown, Louise;
- Ramsay, Craig R;
- Cook, Andrew;
- Armstrong, David;
- Altman, Doug
Publication type:
journal article
Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA2 guidance.
Published in:
2018
By:
- Sones, William;
- Julious, Steven A.;
- Rothwell, Joanne C.;
- Ramsay, Craig Robert;
- Hampson, Lisa V.;
- Emsley, Richard;
- Walters, Stephen J.;
- Hewitt, Catherine;
- Bland, Martin;
- Fergusson, Dean A.;
- Berlin, Jesse A.;
- Altman, Doug;
- Vale, Luke David;
- Cook, Jonathan Alistair
Publication type:
journal article
Incorporating individual historical controls and aggregate treatment effect estimates into a Bayesian survival trial: a simulation study.
Published in:
2019
By:
- Brard, Caroline;
- Hampson, Lisa V;
- Gaspar, Nathalie;
- Le Deley, Marie-Cécile;
- Le Teuff, Gwénaël
Publication type:
journal article
Group sequential tests for delayed responses (with discussion).
Published in:
Journal of the Royal Statistical Society: Series B (Statistical Methodology), 2013, v. 75, n. 1, p. 3, doi. 10.1111/j.1467-9868.2012.01030.x
By:
- Hampson, Lisa V.;
- Jennison, Christopher
Publication type:
Article
A quantitative framework to inform extrapolation decisions in children.
Published in:
Journal of the Royal Statistical Society: Series A (Statistics in Society), 2020, v. 183, n. 2, p. 515, doi. 10.1111/rssa.12532
By:
- Wadsworth, Ian;
- Hampson, Lisa V.;
- Jaki, Thomas;
- Sills, Graeme J.;
- Marson, Anthony G.;
- Appleton, Richard
Publication type:
Article
Many-to-one comparisons after safety selection in multi-arm clinical trials.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0180131
By:
- Hlavin, Gerald;
- Hampson, Lisa V.;
- Koenig, Franz
Publication type:
Article
Combining the Target Trial and Estimand Frameworks to Define the Causal Estimand: An Application Using Real-World Data to Contextualize a Single-Arm Trial.
Published in:
Statistics in Biopharmaceutical Research, 2024, v. 16, n. 1, p. 1, doi. 10.1080/19466315.2023.2190931
By:
- Hampson, Lisa V.;
- Chu, Jufen;
- Zia, Aiesha;
- Zhang, Jie;
- Hsu, Wei-Chun;
- Parzynski, Craig S.;
- Hao, Yanni;
- Degtyarev, Evgeny
Publication type:
Article
Comment on "Biostatistical Considerations When Using RWD and RWE in Clinical Studies for Regulatory Purposes: A Landscape Assessment".
Published in:
Statistics in Biopharmaceutical Research, 2023, v. 15, n. 1, p. 23, doi. 10.1080/19466315.2021.1994459
By:
- Hampson, Lisa V.;
- Degtyarev, Evgeny;
- Tang, Rui;
- Lin, Jianchang;
- Rufibach, Kaspar;
- Zheng, Cheng
Publication type:
Article
A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma.
Published in:
2018
By:
- Cook, Natalie;
- Basu, Bristi;
- Smith, Donna-Michelle;
- Gopinathan, Aarthi;
- Evans, Jeffry;
- Steward, William P;
- Palmer, Daniel;
- Propper, David;
- Venugopal, Balaji;
- Hategan, Mirela;
- Anthoney, D Alan;
- Hampson, Lisa V;
- Nebozhyn, Michael;
- Tuveson, David;
- Farmer-Hall, Hayley;
- Turner, Helen;
- McLeod, Robert;
- Halford, Sarah;
- Jodrell, Duncan
Publication type:
journal article
Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open‐Label, Randomized, Bayesian Noninferiority Trial.
Published in:
Arthritis & Rheumatology, 2021, v. 73, n. 9, p. 1673, doi. 10.1002/art.41730
By:
- Brogan, Paul A.;
- Arch, Barbara;
- Hickey, Helen;
- Anton, Jordi;
- Iglesias, Este;
- Baildam, Eileen;
- Mahmood, Kamran;
- Cleary, Gavin;
- Moraitis, Elena;
- Papadopoulou, Charalampia;
- Beresford, Michael W.;
- Riley, Phil;
- Demir, Selcan;
- Ozen, Seza;
- Culeddu, Giovanna;
- Hughes, Dyfrig A.;
- Dolezalova, Pavla;
- Hampson, Lisa V.;
- Whitehead, John;
- Jayne, David
Publication type:
Article
Designing and evaluating dose-escalation studies made easy: The MoDEsT web app.
Published in:
Clinical Trials, 2020, v. 17, n. 2, p. 147, doi. 10.1177/1740774519890146
By:
- Pallmann, Philip;
- Wan, Fang;
- Mander, Adrian P;
- Wheeler, Graham M;
- Yap, Christina;
- Clive, Sally;
- Hampson, Lisa V;
- Jaki, Thomas
Publication type:
Article
Bayesian survival analysis in clinical trials: What methods are used in practice?
Published in:
Clinical Trials, 2017, v. 14, n. 1, p. 78, doi. 10.1177/1740774516673362
By:
- Brard, Caroline;
- Le Teuff, Gwénaël;
- Le Deley, Marie-Cécile;
- Hampson, Lisa V.
Publication type:
Article
Choosing the target difference ('effect size') for a randomised controlled trial - DELTA2 guidance protocol.
Published in:
2017
By:
- Cook, Jonathan A.;
- Julious, Steven A.;
- Sones, William;
- Rothwell, Joanne C.;
- Ramsay, Craig R.;
- Hampson, Lisa V.;
- Emsley, Richard;
- Walters, Stephen J.;
- Hewitt, Catherine;
- Bland, Martin;
- Fergusson, Dean A.;
- Berlin, Jesse A.;
- Altman, Doug;
- Vale, Luke D.
Publication type:
journal article

Found: 36

Study to evaluate the optimal dose of remifentanil required to ensure apnea during magnetic resonance imaging of the heart under general anesthesia.

Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children.

Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection.

Optimizing the data combination rule for seamless phase II/III clinical trials.

Optimizing the data combination rule for seamless phase II/III clinical trials.

Bayesian methods for the design and interpretation of clinical trials in very rare diseases.

Incorporating prognostic factors into causal estimators: A comparison of methods for randomised controlled trials with a time-to-event outcome.

Clinical Drug Development in Epilepsy Revisited: A Proposal for a New Paradigm Streamlined Using Extrapolation.

Bridging across patient subgroups in phase I oncology trials that incorporate animal data.

Exposure-response modelling approaches for determining optimal dosing rules in children.

A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials.

A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment.

Extrapolation of efficacy and other data to support the development of new medicines for children: A systematic review of methods.

Elicitation of Expert Prior Opinion: Application to the MYPAN Trial in Childhood Polyarteritis Nodosa.

A New Comprehensive Approach to Assess the Probability of Success of Development Programs Before Pivotal Trials.

Bridging the gap: a review of dose investigations in paediatric investigation plans.

Adaptive designs in clinical trials: why use them, and how to run and report them.

A Bayesian decision‐theoretic approach to incorporate preclinical information into phase I oncology trials.

Eliciting judgements about dependent quantities of interest: The SHeffield ELicitation Framework extension and copula methods illustrated using an asthma case study.

Improving the assessment of the probability of success in late stage drug development.

Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593‐606, Sep/Oct 2018., DOI:https://doi.org/10.1002/pst.1873

Assurance methods for designing a clinical trial with a delayed treatment effect.

Correction to: Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA2 guidance.

DELTA<sup>2</sup> guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.

Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA<sup>2</sup> guidance.

Incorporating individual historical controls and aggregate treatment effect estimates into a Bayesian survival trial: a simulation study.

Group sequential tests for delayed responses (with discussion).

A quantitative framework to inform extrapolation decisions in children.

Many-to-one comparisons after safety selection in multi-arm clinical trials.

Combining the Target Trial and Estimand Frameworks to Define the Causal Estimand: An Application Using Real-World Data to Contextualize a Single-Arm Trial.

Comment on "Biostatistical Considerations When Using RWD and RWE in Clinical Studies for Regulatory Purposes: A Landscape Assessment".

A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma.

Mycophenolate Mofetil Versus Cyclophosphamide for Remission Induction in Childhood Polyarteritis Nodosa: An Open‐Label, Randomized, Bayesian Noninferiority Trial.

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app.

Bayesian survival analysis in clinical trials: What methods are used in practice?

Choosing the target difference ('effect size') for a randomised controlled trial - DELTA<sup>2</sup> guidance protocol.