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- Title
Lipids: The plasma membrane code.
- Authors
Futerman, Anthony H.; Schuldiner, Maya
- Abstract
The article discusses the unanticipated mode of regulation of sphingolipid and endocytosis metabolism in new epistatic map of almost 400 genes. Researchers evaluated genetic interactions for 374 yeast genes whose products have functions influencing membrane function or localized to the plasma membrane. Researchers applied ingenious genetic methods to pass all deletion strains of the aforementioned proteins against each other, making all possible double mutation.
- Subjects
SPHINGOLIPIDS; ENDOCYTOSIS; CELL membranes; CELL physiology; YEAST
- Publication
Nature Chemical Biology, 2010, Vol 6, Issue 7, p487
- ISSN
1552-4450
- Publication type
Article
- DOI
10.1038/nchembio.397