We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cardiopulmonary Exercise Capacity and Ventilation Effectiveness in Patients after Clinical Cure of Acute Irritant Gas Poisoning.
- Authors
Yan, Rong; Yang, Wenlan; Liu, Jinming; Gao, Beilan; Guo, Kongrong; Sun, Daoyuan
- Abstract
The aim of this study is to assess the medium to long-term effect of acute irritant gas poisoning on cardiopulmonary exercise function in patients after clinical cure. Fourteen patients after an average of 18.5 months of clinical cure of acute irritant gas poisoning were recruited, and 14 healthy individuals were selected as control. All subjects were examined by resting pulmonary function testing (RPFT), cardiopulmonary exercise testing (CPET), and arterial blood gas (ABG) analysis. No statistically significant differences were found between poisoning and control groups for baseline parameters (age, height, and weight) or ABG values (pH, PaO, PaCO, and SaO) ( P > 0.05). For most RPFT parameters, including FEV/FVC, FEV, FEV%pred, RV/TLC, DLCO%, and FVC%, no statistically significant differences were observed between poisoning and control groups ( P > 0.05). However, MVV% was significantly lower in poisoning group compared with healthy individuals ( P < 0.05). Statistically significant differences were observed for some CPET parameters, including peak VO, peak VO/kg, peak VE, and lowest VE/VCO ( P < 0.05), and peak load, V/ V, and peak PCO ( P < 0.01) between the two groups. However, there were no statistically significant differences in peak VO%pred or peak O pulse between poisoning and control groups ( P > 0.05). Compared with controls, patients with acute irritant gas poisoning had decreased cardiopulmonary exercise capacity and ventilation effectiveness after clinical cure.
- Subjects
BLOOD gases analysis; CARDIOPULMONARY fitness measurement; DRUG efficacy; POISONOUS gases; VENTILATION monitoring
- Publication
Cell Biochemistry & Biophysics, 2015, Vol 71, Issue 2, p789
- ISSN
1085-9195
- Publication type
Article
- DOI
10.1007/s12013-014-0264-2