We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Nickel-Catalyzed Monoarylation of Ammonia.
- Authors
Borzenko, Andrey; Rotta-Loria, Nicolas L.; MacQueen, Preston M.; Lavoie, Christopher M.; McDonald, Robert; Stradiotto, Mark
- Abstract
Structurally diverse (hetero)aryl chloride, bromide, and tosylate electrophiles were employed in the Ni-catalyzed monoarylation of ammonia, including chemoselective transformations. The employed JosiPhos/[Ni(cod)2] catalyst system enables the use of commercially available stock solutions of ammonia, or the use of ammonia gas in these reactions, thereby demonstrating the versatility and potential scalability of the reported protocol. Proof-of-principle experiments established that air-stable [(JosiPhos)NiCl2] precatalysts can be employed successfully in such transformations.
- Subjects
NICKEL; AMMONIA gas; ARYL chlorides; ELECTROPHILES; CHEMOSELECTIVITY; ANILINE derivatives; PALLADIUM
- Publication
Angewandte Chemie, 2015, Vol 127, Issue 12, p3844
- ISSN
0044-8249
- Publication type
Article
- DOI
10.1002/ange.201410875