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- Title
Prevalence and Risk Factors of Healthcare-Associated Infections among Hospitalized Pediatric Patients: Point Prevalence Survey in Thailand 2021.
- Authors
Moolasart, Visal; Srijareonvijit, Chaisiri; Charoenpong, Lantharita; Kongdejsakda, Winnada; Anugulruengkitt, Suvaporn; Kulthanmanusorn, Anond; Thienthong, Varaporn; Usayaporn, Sang; Kaewkhankhaeng, Wanwisa; Rueangna, Oranat; Sophonphan, Jiratchaya; Manosuthi, Weerawat; Tangcharoensathien, Viroj
- Abstract
Background: Healthcare-associated infections (HAIs) pose a grave threat to patient safety, morbidity, and mortality, contributing to antimicrobial resistance. Thus, we estimated the point prevalence, risk factors, types, and pathogens of HAIs in hospitalized pediatric patients. Methods: A point prevalence survey (PPS) of HAIs in hospitalized pediatric patients < 18 years old was conducted from March to May 2021. Outcomes, risk factors, and types of HAIs associated with HAIs in 41 hospitals across Thailand were collected. Results: The prevalence of HAIs was 3.9% (95% CI 2.9–5.0%) (56/1443). By ages < 1 month, 1 month–2 years, 2–12 years, and 12–18 years, the prevalence of HAIs was 4.2%, 3.3%, 4.1%, and 3.0%, respectively (p = 0.80). Significant independent risk factors were extended hospital length of stay (LOS) and central venous catheter (CVC) use. Compared to an LOS of <4 days, LOSs of 4–7 days, 8–14 days, and >14 days had adjusted odds ratios (aORs) of 2.65 (95% CI 1.05, 6.68), 5.19 (95% CI 2.00, 13.4), and 9.03 (95% CI 3.97, 20.5), respectively. The use of a CVC had an aOR of 2.45 (95% CI 1.06–5.66). Lower respiratory tract infection (LRTI) was the most common HAI type (46.4%: 26/56). The highest prevalence of HAIs was predominantly observed in LRTI diagnoses, with the highest among these in the <1 month age category at 2.3% (17/738). Conclusion: The prevalence of HAIs in hospitalized pediatric patients was 3.9%. Extended LOS and use of CVC were HAI risk factors. A strategy for reducing LOS and reviewing insertion indications or the early planned removal of a CVC was implemented. The surveillance of HAIs stands as a cornerstone and fundamental component of IPC, offering invaluable insights that enhance hospital IPC interventions aimed at preventing HAIs.
- Subjects
THAILAND; RISK assessment; PUBLIC health surveillance; STATISTICAL models; TRACHEOTOMY; CROSS infection; RESPIRATORY infections; MULTIPLE regression analysis; FISHER exact test; NEONATAL intensive care units; HOSPITAL admission &; discharge; BACTEREMIA; DISEASE prevalence; DESCRIPTIVE statistics; AGE distribution; CHI-squared test; ENDOTRACHEAL tubes; NEONATAL intensive care; URINARY catheters; MULTIVARIATE analysis; HOSPITAL care of newborn infants; ODDS ratio; PEDIATRICS; INTENSIVE care units; CENTRAL venous catheters; STATISTICS; SEPSIS; CONFIDENCE intervals; LENGTH of stay in hospitals; DATA analysis software; SURGICAL site infections; COMPARATIVE studies; HOSPITAL care of children; HOSPITAL care of teenagers
- Publication
Children, 2024, Vol 11, Issue 6, p738
- ISSN
2227-9067
- Publication type
Article
- DOI
10.3390/children11060738