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- Title
Induction of Subcutaneous Nodules in Rabbits with the SE Polyoma Virus.
- Authors
EDDY, BERNICE E.; STEWART, SARAH E.; KIRSCHSTEIN, RUTH L.; YOUNG, RALPH D.
- Abstract
THE SE polyoma virus grown in mouse embryo cell cultures is capable of inducing a wide spectrum of histologically different neoplasms in hybrid (C3Hf × AKR)F11 and randomly bred Swiss mice2, and sarcomas and angiomatous lesions in hamsters3, and rats4, if injections are made when the animals are new-born. Tumours in these animals increase in size and number and eventually kill the animals. Contrary to experience with these rodents, new-born rabbits of mongrel breed reacted by developing multiple subcutaneous nodules that later regressed.
- Publication
Nature, 1959, Vol 183, Issue 4663, p766
- ISSN
0028-0836
- Publication type
Article
- DOI
10.1038/183766a0