We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Late occurrence of cysts in autosomal dominant medullary cystic kidney disease.
- Authors
Neumann, H P; Zäuner, I; Strahm, B; Bender, B U; Schollmeyer, P; Blum, U; Rohrbach, R; Hildebrandt, F
- Abstract
Medullary cystic kidney disease (MCD) is characterized by multiple renal cysts at the corticomedullary boundary area, by autosomal dominant inheritance, and by onset of chronic renal failure in the third decade of life. We report on a family with three affected individuals of both sexes in two generations presenting with end-stage renal failure at age 22-31 years. Primarily diagnoses considered included unclassified hereditary nephropathy and autosomal dominant polycystic kidney disease. Careful evaluation of all findings, initiated after investigation of renal morphology with CT, revealed features characteristic for MCD and led to the final diagnosis of MCD. We conclude that MCD is an important differential diagnosis for polycystic kidney disease in young adults with end-stage renal failure. Establishing the correct diagnosis has considerable impact for genetic counselling.
- Publication
Nephrology Dialysis Transplantation, 1997, Vol 12, Issue 6, p1242
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/12.6.1242