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- Title
Multiple lymphadenopathies in eosinophilic granulomatosis with polyangiitis: Differentiating from IgG4-related lymphadenopathy.
- Authors
Jun-ichi Kurashina; Yasuhiro Shimojima; Dai Kishida; Takanori Ichikawa; Takeshi Uehara; Yoshiki Sekijima
- Abstract
This article presents a case study of a 75-year-old man with eosinophilic granulomatosis with polyangiitis (EGPA) who had multiple lymphadenopathies. The lymph node tissue biopsy revealed features of both EGPA and IgG4-related lymphadenopathy (IgG4-LAD). While IgG4-LAD is a distinct clinical category, some autoimmune diseases like EGPA can have similar lymphadenopathies. The presence of IgG4-positive plasma cells suggests a potential connection between EGPA and IgG4-related disease (IgG4-RD). The article also mentions the coexistence of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis and IgG4-RD in some cases, as well as the role of hypocomplementemia in disease activity.
- Subjects
CHURG-Strauss syndrome; PLASMA cell diseases; NOSOLOGY; PLASMA cells; GRANULOMATOSIS with polyangiitis; HYPEREOSINOPHILIC syndrome
- Publication
Modern Rheumatology Case Reports, 2024, Vol 8, Issue 2, p318
- ISSN
2472-5625
- Publication type
Article
- DOI
10.1093/mrcr/rxae022