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- Title
磁共振扩散加权成像对宫颈癌诊断价值及其与临床病理特征的关系研究.
- Authors
杨皓; 吴勘华; 宋恬; 孙荣跃; 殷士蒙
- Abstract
Objective: To study the diagnostic value of magnetic resonance diffusion-weighted imaging(DWI) in cervical cancer and its relationship with clinicopathological features. Methods: 90 cases of patients with cervical cancer who were treated in our hospital from May 2016 to May 2018 were enrolled as the study group. There were 69 cases of squamous cell carcinoma and 21 cases of adenocarcinoma. Another 90 patients without cervical cancer who underwent cervical examination for other reasons were selected as the control group. The two groups of patients underwent conventional magnetic resonance imaging(MRI) plain scan and DWI examination.The MRI imaging features of the two groups were observed. Apparent diffusion coefficient(ADC) values were compared between the study group and the control group, different pathological types and clinicopathological features of cervical cancer patients. Receiver operating characteristic(ROC) curve was used to evaluate the diagnostic value of DWI in cervical cancer. The relationship between ADC value and clinicopathological features of cervical cancer patients was analyzed. Results: MRI images of the study group and the control group all met the requirements of diagnosis and measurement, without significant artifacts and distortion. The lesions in the study group were located in the cervix, and their signal characteristics T1 weighted imaging(T1 WI) showed equal signal. T2-weighted imaging(T2 WI) showed slightly high/high signal, and DWI showed a high signal mass, and the boundary was clear. The ADC value of DWI in the study group was lower than that in the control group(P<0.05). The ADC value of DWI in squamous cell carcinoma patients was also significantly lower than that in adenocarcinoma patients(P <0.05). The ROC curve showed that the AUC of DWI in examination for differential diagnosis of cervical cancer and non cervical cancer, squamous cell carcinoma and adenocarcinoma were 0.912 and 0.827 respectively. The ADC values of cervical cancer patients with no lymph node metastasis, stage I-II, medium/high differentiation and intercellular proportion of tumor cells<70% were higher than those of cervical cancer patients with lymph node metastasis, stage III-VI,poorly differentiation and intercellular proportion of tumor cells ≥70%(P <0.05). Conclusion: DWI has a high diagnostic value for cervical cancer. DWI imaging parameters ADC value is closely related to the clinicopathological features of cervical cancer. To some extent, it can help doctors to understand the pathological classification, clinicopathological stage, degree of differentiation and lymph node metastasis of cervical cancer.
- Publication
Progress in Modern Biomedicine, 2019, Vol 19, Issue 10, p1870
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2019.10.013