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- Title
中国西北地区胃粘膜肠上皮化生危险因素调查.
- Authors
柯丽; 张迪; 陈瑜; 张林慧; 朱绍华; 王安辉; 尚磊; 时永全
- Abstract
Objective: To find out the risk factors of gastric intestinal metaplasia in northwest of China. Methods: A case-control study was conducted with a well-designed questionnaire, all patients were from the clinics of Xijing hospital with the results of gastroscopy and/or gastric mucosal pathology. All patients were enrolled in the present study from August 2014 to April 2015. H. pylori infection was measured by 13C- or 14C-urea breath test or by rapid urease test. Results: A total of 1800 cases were enrolled in the study, among them. 261 cases were with gastric intestinal metaplasia. The multivariate analysis showed that the risk factors of intestinal metaplasia were age ≤60yr (OR, 2.317; 95% CI 1.668-3.220; P< 0.001), H. pylori infection (OR. 2.911; 95% CI 2.339-3.623; P< 0.001), smoking (OR. 2.322; 95% CI 1.553-3.470; P< 0.001), family history of gastric cancer (OR. 2.229; 95% CI 1.444-3.439; P< 0.001). high salt diet (OR. 1.557; 95% CI 1.118-2.168; P=0.009), spicy food (OR. 1.551; 95% CI 1.121-2.147; P=0.005) and bile reflux (OR. 1.851; 95% CI 1.135-3.021: P=0.014). Conclusions: The risk factors of intestinal metaplasia in northwest of China were patients with age ≤60yr, H. pylori infection, smoking, family history of gastric cancer, high salt diet, spicy food and bile reflux.
- Publication
Progress in Modern Biomedicine, 2016, Vol 16, Issue 34, p6639
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2016.34.010