We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Aortic Valve Stenosis and Cardiac Amyloidosis: An Underestimated Coexistence.
- Authors
Oikonomou, Dimitrios; Liontou, Catherine; Triantafyllou, Konstantinos
- Abstract
Coexistence of aortic valve stenosis (AS) and cardiac amyloidosis (CA) is frequent in the elderly as both conditions increase with age. Wild type transthyretin (TTR) amyloidosis is the most common type of amyloidosis in AS cohorts. Cardiac amyloidosis and AS share common clinical characteristics making diagnosis of dual pathology challenging. However, certain features should raise suspicion of CA presence in AS patients leading to specific imaging modalities to confirm diagnosis. Dual pathology (AS & CA) increase mortality risk and prompt diagnosis is crucial. Novel pharmacological agents targeted for TTR CA should be initiated to improve prognosis. The role of the Heart Team for decision-making in these cases regarding the optimal management of AS is crucial. Transcatheter aortic valve replacement may be the preferred procedure in these highrisk patients.
- Subjects
CARDIAC amyloidosis; AORTIC stenosis; HEART valves; HEART valve prosthesis implantation
- Publication
Rhythmos, 2022, Vol 17, Issue 3, p53
- ISSN
1792-7919
- Publication type
Article