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- Title
Oral Microbiota, Bacterial Infections, Antibiotic Prescriptions, and Antimicrobial Resistance in Children.
- Authors
Amato, Alessandra
- Abstract
The primary cause of orofacial infections is related to dental problems, with dental caries and their associated conditions, such as pulpitis, pulp necrosis, apical periodontitis, and periapical abscess, being the most prevalent [[5]]. This has led to the overuse and misuse of antibiotics for nonindicated clinical conditions, such as pain relief, irreversible pulpitis, and localized dentoalveolar abscess, as well as prescribing broad-spectrum antibiotics for infections that can be treated with narrow-spectrum antibiotics, prescribing antibiotics for long periods, and adopting inappropriate dosing regimens, exposing pediatric dental patients to a multitude of potential adverse reactions [[9], [25]]. Another consequence of periapical infection is the formation of a pulp polyp, a chronic hyperplastic lesion forming in the pulp chamber due to long-standing infection [[3]]. Therefore, early treatment of odontogenic infections can prevent these morbidities; however, antibiotic administration may be needed when the infection becomes severe [[9]].
- Subjects
BACTERIAL diseases; DRUG resistance in microorganisms; MEDICAL personnel; ANTIBIOTICS; DEVELOPMENTAL defects of enamel; AMELOBLASTS
- Publication
Microorganisms, 2023, Vol 11, Issue 8, p1927
- ISSN
2076-2607
- Publication type
Article
- DOI
10.3390/microorganisms11081927