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- Title
Fournier's gangrene originating from the perianal region or the urogenital area: does it make a difference?
- Authors
Cengiz, Fevzi; Gur, Emine Ozlem; Atay, Yigit Doganay; Kamer, Kemal Erdinc; Bozok, Yeliz Yilmaz; Bag, Halis; Gungor, Feyyaz; Haciyanli, Mehmet
- Abstract
Objective: Fournier's gangrene (FG) is a rare and serious disorder which is associated with high mortality. In the literature, there is no study evaluating clinician-, patient- and disease-related factors affecting disease outcomes according to aetiological variation in FG. In our study, laboratory results and Uludag Fournier's Gangrene Severity Index (UFGSI) score, clinical characteristics and mortality rates were compared between FG originating from perianal or from urogenital regions. Method: Platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) and UFGSI risk scores were calculated in patients with FG at presentation to the emergency department. The patients were assigned to two groups according to FG aetiology. Results: It was observed that the number of debridement interventions and the need for colostomy were significantly greater in the perianal FG group, while the need for flap or reconstruction was significantly (p=0.002) higher in the genitourinary FG group. No significant difference was detected in mortality between groups and the difference in aetiology had no significant effect on the results of the neutrophil-to-lymphocyte ratio, LRINEC or UFGSI scores. Conclusion: Laboratory results and UFGSI score were helpful in assessing disease severity independently from aetiology. The higher number of debridement interventions to protect anal function in the perianal group and the greater need for reconstructive surgery in the urogenital group were identified as factors that prolonged length of hospital stay.
- Subjects
NEUTROPHIL lymphocyte ratio; ANUS; T-test (Statistics); RECEIVER operating characteristic curves; STATISTICAL significance; SEVERITY of illness index; SYMPTOMS; RETROSPECTIVE studies; MANN Whitney U Test; CHI-squared test; DESCRIPTIVE statistics; PERINEUM; LONGITUDINAL method; PLATELET lymphocyte ratio; NECROTIZING fasciitis; COLOSTOMY; SURGICAL flaps; FOURNIER gangrene; DEBRIDEMENT; PLASTIC surgery; LENGTH of stay in hospitals; DATA analysis software; DISEASE risk factors
- Publication
Journal of Wound Care, 2024, Vol 33, Issue Sup6, pS8
- ISSN
0969-0700
- Publication type
Article
- DOI
10.12968/jowc.2021.0278