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- Title
The Role of GC-Rich Sequences from the Promoter Region of the Drosophila melanogaster yellow Gene in the Enhancer- Dependent Activation of Transcription.
- Authors
Kostyuchenko, M. V.; Golovnin, A. K.; Georgiev, P. G.; Melnikova, L. S.
- Abstract
It is shown that mutations in two GC-rich sequences (GC-boxes) from the promoter region of the yellow gene during enhancer-dependent transcription activation do not affect the basal level of the yellow gene transcription but destabilize the interaction between the enhancers and the promoter.
- Subjects
NUCLEOTIDE sequence; DROSOPHILA melanogaster; TRANSCRIPTION factors; GENES; GENETIC mutation
- Publication
Doklady Biochemistry & Biophysics, 2018, Vol 482, Issue 1, p255
- ISSN
1607-6729
- Publication type
Article
- DOI
10.1134/S1607672918050071