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- Title
Characterizing cutaneous metastatic destinations of renal cell carcinoma.
- Authors
Williams, Josiah A.; White, Jonathan C.; Feldman, Steven R.
- Abstract
Four cutaneous lesions were described as red or erythematous papules or nodules, resembling the most typical appearance of cutaneous metastases for renal cell carcinoma.[2] One lesion was described as an erythematous plaque with central dark scale. Metastatic disease is present in up to 33% of newly diagnosed renal cell carcinomas (RCC).[1] The most common sites of spread are lung, bone, abdomen, and brain, but skin metastases may be present in up to 8% of cases.[[1]] Cutaneous metastatic lesions may have varying appearances but typically present as solitary black, brown, or violaceous papules, nodules, or plaques that grow rapidly.[2] Since metastatic lesions may be the first presentation of underlying malignancy and prompt recognition of metastatic disease could expedite treatment, we sought to characterize the most frequent cutaneous and subcutaneous metastatic destinations of renal cell carcinoma.[3] Upon Wake Forest School of Medicine Institutional Review Board approval, we performed a retrospective chart review of patients with RCC metastatic to the skin. Five lesions were described as deeper palpable nodules with or without superficial discoloration, suggesting lesions to be primarily located in the subcutaneous tissue.
- Subjects
RENAL cell carcinoma; METASTASIS; INSTITUTIONAL review boards
- Publication
International Journal of Dermatology, 2023, Vol 62, Issue 7, pe400
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1111/ijd.16431