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- Title
Cyclosporine A as a Primary Treatment for Panniculitis-like T Cell Lymphoma: A Case with a Long-Term Remission.
- Authors
Won Sup Lee; Ji-Hyen Hwang; Moon Jin Kim; Se-Il Go; Anna Lee; Haa-Na Song; Min Jeong Lee; Myung Hee Kang; Hoon-Gu Kim; Jeong-Hee Lee
- Abstract
Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous lymphoma characterized by an infiltration of subcutaneous tissue by neoplastic T cells, similar to panniculitis. It is well-established that patients who are diagnosed with SPTL usually respond poorly to chemotherapy, showing fatal outcome. As a first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the treatment of SPTL, the efficacy of cyclosporine A has been recently reported in relapsed SPTL after anthracycline-based chemotherapy. However, it is still not clear whether cyclosporine A can be used as a first-line treatment against SPTL. Here, we report a case of SPTL, which achieved complete remission for nine years after first-line cyclosporine A therapy. This study suggests that cyclosporine A can induce a complete long-term remission as a first-line treatment.
- Subjects
CYCLOSPORINE; LYMPHOMA treatment; ANTHRACYCLINES; T cells
- Publication
Cancer Research & Treatment, 2014, Vol 46, Issue 3, p312
- ISSN
1598-2998
- Publication type
Case Study
- DOI
10.4143/crt.2014.46.3.312