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- Title
Mediastinitis secondary to invasive infection by group A Streptococcus in Spain.
- Authors
Mellado-Sola, I.; Cobo-Vázquez, E.; Calvo-Fernandez, A.; Cervantes, E.; Coca, A.; Calderón-Llopis, B.; Saavedra-Lozano, J.; Calvo, C.; PedGAS-net group; Grandioso, D.; Aguilera, D.; Rincón, E.; Jové, A.; Cercenado, E.; Sanz Santaeufemia, F. J.; Gónzalez, M. J.; Sánchez, E.; Blázquez, D.; Manzanares, A.; Reinoso, T.
- Abstract
This study describes 5 mediastinitis cases secondary to invasive group A Streptococcus (iGAS) disease in a recent outbreak in Spain. Among 398 iGAS cases between January 2019—March 2023, 5 (1.3%) were mediastinitis, 4 occurring in December 2022, all secondary to pneumonia or deep neck infection. We outline the clinical outcome with a review of the scarce pediatric literature. Conclusion: mediastinistis is a rare but severe complication of iGAS and a high level of suspicion is required to diagnose it. What is Known: • Group A Streptococcus can cause invasive and severe infections in children. • Mediastinitis is a severe complication from some bacterial infections, mainly secondary due to deep-neck abscesses. What is New: • Mediastinitis is an unrecognized complication due to an invasive group A Streptococcus (iGAS) infection. • In cases of a deep-neck abscess or complicated pneumonia a high clinical suspicion of iGAS mediastinitis is required, especially when the clinical course is not favorable.
- Subjects
SPAIN; MEDIASTINITIS; STREPTOCOCCAL diseases; BACTERIAL diseases; COMPLEX organizations; DISEASE outbreaks; STREPTOCOCCUS
- Publication
European Journal of Pediatrics, 2024, Vol 183, Issue 1, p503
- ISSN
0340-6199
- Publication type
Article
- DOI
10.1007/s00431-023-05288-3