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- Title
THE IMMUNE RESPONSE TO HETEROLOGOUS RED CELLS IN MICE IV. INDUCTION OF UNRESPONSIVENESS TO WEAKLY IMMUNOGENIC RED CELLS BY CYCLOPHOSPHAMIDE AND CORTISONE ACETATE.
- Authors
Dietrich, F. M.; Dukor, P.
- Abstract
The article focuses on a study in which recovery from cyclophosphamide-induced unresponsiveness to multi-species erythrocytes in adult mice was found to depend on immunogenicity of the red cells tested. Previous studies from this laboratory revealed differences in the relative immunogenicity of various heterologous erythrocytes. As judged by antigen dose-antibody response relations, red cells from gerbil, hamster and guinea-pig proved to be genuinely weaker immunogens in mice than erythrocytes from cotton rat, rat and sheep.
- Subjects
CYCLOPHOSPHAZENES; PHOSPHAZO compounds; ERYTHROCYTES; BLOOD cells; XENOGRAFTS; IMMUNOGENETICS
- Publication
Clinical & Experimental Immunology, 1968, Vol 3, Issue 8, p783
- ISSN
0009-9104
- Publication type
Article