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- Title
Ketamine as a bridging agent in opioid maintenance therapy.
- Authors
Arora, Siddharth S.
- Abstract
The article discusses role of ketamine, an N-methyl-D-aspartate receptor antagonist, classified as a dissociative anesthetic, which used for analgesia in adults and for sedation in pediatric patients, as a bridging agent in opioid maintenance therapy. It states ketamine impacts the physical dependence on opioids, and addresses the psychological factors of addiction, and mentions that ketamine's influence on the dopamine and serotonin systems enables rapid onset of antidepressant properties.
- Subjects
OPIOID abuse; KETAMINE; OPIOIDS; DRUG therapy; ANALGESICS; PHYSIOLOGICAL effects of antidepressants; PHYSIOLOGY
- Publication
American Journal on Addictions, 2018, Vol 27, Issue 1, p47
- ISSN
1055-0496
- Publication type
journal article
- DOI
10.1111/ajad.12672