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- Title
Data Extraction Errors in Meta-analyses That Use Standardized Mean Differences.
- Authors
Gotzsche, Peter C.; Hróbjartsson, Asbjorn; Marić, Katja; Tendal, Britta
- Abstract
This article presents the results of a study looking at how meta-analysis of clinical trials which used different means of measurement, can be transformed into a uniform scale; the standardized mean difference (SMD) scale. Further, the study wanted to see how reliable the resulting meta-analyses are from the SMD. The high proportion of meta-analyses based on SMDs that showed errors indicated that data extraction was the probable cause for error rates and this can negate or even reverse the findings of a study. The authors say that all readers and policy makers need to take note and approach meta-analyses with caution.
- Subjects
META-analysis; CLINICAL trials; STATISTICS; DATA editing; MEDICAL statistics; METADATA; ELECTRONIC data processing
- Publication
JAMA: Journal of the American Medical Association, 2007, Vol 298, Issue 4, p430
- ISSN
0098-7484
- Publication type
Article