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- Title
An angiographic study of prevalence of coronary artery disease in patients with peripheral arterial disease.
- Authors
G., Somashekhara; Rao, Murali; H., Anuradha
- Abstract
Objective: To study predictors and prevalence of CAD in patients with PAD. Background: There is very little data on prevalence of angiographically proven coronary artery disease (CAD) in patients with peripheral arterial disease (PAD). Methods: We evaluated prospectively, 216 consecutive patients with PAD who were referred for peripheral angiography. After obtaining informed consent all patients underwent coronary angiography in addition to peripheral angiography. Results: The mean age of the patients was 54± 10 years. 93% of patients were males. Smoking was the most common risk factor (n=158 72%), followed by dyslipidemia (n=108 50%), diabetes (n=88, 40%) and hypertension (n=82, 37%). Majority of the patients had femoral artery lesion (n=105,48%) followed by iliac(n=71,32%), distal lower limb (n=60,28%), aortic(n=24,11%)and renal artery stenosis.(n=7,3%). Significant CAD, defined as 50% or more stenosis of a major epicardial coronary artery was seen in 86(40%). patients. CAD was most likely in patients with aortic (64%), followed by patients with renal artery stenosis (57%), and lower limb (36%). Patients with CAD were significantly older (57.88. years vs. 51.6 years P<0.001), more likely to be diabetic (56% vs. 18% P<0.001), hypertensive (54 vs. 18% P<0.001), dyslipidemic (70% vs. 37%, P<0.001) and smokers (73% vs. 43%;P<0.001). Conclusion: CAD is common (40%) in patients with PAD and is more common in patients with significant stenosis in aorta, followed by renal, and distal lower limb arterial disease. In comparison, CAD is least common in patients with distal lower limb disease. Increasing age, diabetes, and hypertension, dyslipidemia and smoking were significantly commoner in patients with concomitant CAD.
- Subjects
PERIPHERAL vascular diseases; CORONARY artery disease; ANGIOGRAPHY; INFORMED consent (Medical law); ARTERIAL diseases; TAKAYASU arteritis; RENAL artery diseases
- Publication
European Journal of Cardiovascular Medicine, 2022, Vol 12, Issue 1, p11
- ISSN
2042-4884
- Publication type
Article