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- Title
Effects of acute, intermittent exercise in hypoxic environments on the release of cardiac troponin.
- Authors
Li, F.; Hu, Y.; Nie, J.; Fu, F.H.
- Abstract
The purpose of this study was to examine the effects of acute, intermittent exercise performed in hypoxic environments on the release of cardiac troponin ( cTn). Ten well-trained, male marathon runners (22.1 ± 2.6 years, 64.0 ± 4.9 kg and 177.3 ± 3.9 cm) completed three intermittent exercise protocols under normoxic (trial N) and hypoxic (trial AH and RH) conditions. In trial N, the fraction of inspiration oxygen ( FIO2) was 21.0% and exercise intensity was 90% and 50% normoxic velocity of VO2max ( vVO2max). In trial AH, FIO2 was 14.4% (simulated altitude of 3000 m) and exercise intensity was 90% and 50% normoxic vVO2max. In trial RH, FIO2 was 14.4% and exercise intensity was 90% and 50% hypoxic vVO2max. High-sensitivity cardiac troponin T ( hs- cTnT) and cardiac troponin I ( cTnI) were measured pre- and 0, 2, 4, and 24 h post-exercise. Hs- cTnT was elevated in all three trials, peaking at 2 to 4 h and returning to the baseline 24 h post-exercise. CTnI increased in trial AH, peaking at 2 to 4 h and returning below the detection limit 24 h post-exercise. It is concluded that the stimulus of hypoxia did not in and of itself induce more cTn to be released, but exercise intensity could affect this response in hypoxic environments.
- Subjects
ACTIVE oxygen in the body; ALTITUDES; HYPOXEMIA; ECOLOGY; EXERCISE; HEART beat; PROBABILITY theory; STATISTICS; T-test (Statistics); DATA analysis; RANDOMIZED controlled trials; REPEATED measures design; OXYGEN consumption; BLIND experiment; DATA analysis software; TROPONIN; DESCRIPTIVE statistics; ONE-way analysis of variance
- Publication
Scandinavian Journal of Medicine & Science in Sports, 2016, Vol 26, Issue 4, p397
- ISSN
0905-7188
- Publication type
Article
- DOI
10.1111/sms.12463