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- Title
Autologous melanocyte-keratinocyte suspension in the treatment of vitiligo.
- Authors
El-Zawahry, B. M.; Zaki, N. S.; Bassiouny, D. A.; Sobhi, R. M.; Zaghloul, A.; Khorshied, M. M.; Gouda, H. M.
- Abstract
In stable vitiligo, several techniques of autologous transplantation of melanocytes are used. Autologous melanocyte transplantation of non-cultured melanocytes is one of those techniques with variable reported outcomes. The objective of this study was to evaluate the response to autologous melanocyte-keratinocytes suspension transplantation in cases of stable vitiligo. A total of 25 cases of vitiligo were treated by autologous melanocyte-keratinocytes suspension transplantation. After 6-17 months, patients' response was evaluated according to the extent of pigmentation (excellent 90-100%, good 50-89%, fair 20-49% and poor response <20%). Of the 25 patients treated, 22 continued the follow-up period. Five (23%) patients showed excellent response, 7 (32%) good, 6 (27%) fair and 4(18%) showed poor response. Unlike transplantation of cultured melanocytes, which requires experience in culture technique, autologous melanocyte-keratinocytes suspension transplantation is an easy economic technique, which may be used in resistant areas of stable vitiligo.
- Subjects
MELANOCYTES; AUTOTRANSPLANTATION; VITILIGO; KERATINOCYTES; PIGMENTATION disorders; EPITHELIAL cells; THERAPEUTICS
- Publication
Journal of the European Academy of Dermatology & Venereology, 2011, Vol 25, Issue 2, p215
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1111/j.1468-3083.2010.03759.x