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- Title
Cancer Incidence among an HIV-infected Cohort.
- Authors
Johnson, C. C.; Wilcosky, T.; Kvale, P.; Rosen, M.; Stansell, J.; Glassroth, J.; Reichman, L.; Wallace, J.; Markowitz, N.; Thompson, J. E.; Hopewell, P.
- Abstract
Malignancies, particularly Kaposi's sarcoma and non-Hodgkin's lymphoma (NHL), are associated with human immunodeficiency virus (HIV) infection. Cancer incidence among 1,073 asymptomatic HIV-infected individuals from the Pulmonary Complications of HIV Infection Study cohort, persons from six states followed from 1988 to 1994, was examined. Total cancer incidence was 3.99/100 person-years; for Kaposi's sarcoma, incidence was 2.64 cases/100 person-years, and for NHL, it was 1.18 cases/100 person-years. Total cancer (n = 156 cases) was higher among nonblacks than among blacks (rate ratio = 2.8, 95% confidence interval 1.3–6.1), with similar results for Kaposi's sarcoma and NHL. The rate of lung cancer (n = 5) among white, homosexual/bisexual males was 0.18 per 100 person-years, suggesting a high risk of lung cancer. Am J Epidemiol 1997;146:470-5.
- Subjects
UNITED States; DISEASE incidence; KAPOSI'S sarcoma; LYMPHOMAS; COHORT analysis; HIV-positive persons
- Publication
American Journal of Epidemiology, 1997, Vol 146, Issue 6, p470
- ISSN
0002-9262
- Publication type
Article