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- Title
Strategies for Personalized Medicine-Based Research and Implementation in the Clinical Workflow.
- Authors
Lieb, W; Völzke, H; Pulley, J M; Roden, D M; Kroemer, H K
- Abstract
The decoding of the human genome, paralleled by the development of high-throughput technologies to obtain large-scale molecular data (e.g., information on genetic variations, transcription levels, and metabolite concentrations) is providing new insights into the molecular basis of common diseases and the causes of variability in drug response. This article presents strategies to incorporate this new knowledge into research and clinical workflow.
- Subjects
INDIVIDUALIZED medicine; HUMAN genome; MEDICAL research; HIGH throughput screening (Drug development); HUMAN genetic variation; GENETIC transcription
- Publication
Clinical Pharmacology & Therapeutics, 2012, Vol 92, Issue 4, p443
- ISSN
0009-9236
- Publication type
Article
- DOI
10.1038/clpt.2012.119