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- Title
Diabetic nephropathy is not associated with the dinucleotide repeat polymorphism upstream of the aldose reductase (ALR2) gene but with erythrocyte aldose reductase content in Japanese subjects with type 2 diabetes.
- Authors
Maeda, Shiro; Haneda, Masakazu; Yasuda, Hitoshi; Tachikawa, Tomokazu; Isshiki, Keiji; Koya, Daisuke; Terada, Masahiko; Hidaka, Hideki; Kashiwagi, Atsunori; Kikkawa, Ryuichi; Maeda, S; Haneda, M; Yasuda, H; Tachikawa, T; Isshiki, K; Koya, D; Terada, M; Hidaka, H; Kashiwagi, A; Kikkawa, R
- Abstract
Studies whether diabetic nephropathy is associated with the dinucleotide repeat polymorphism upstream of the aldose reductase (ALR2) gene. Association of the genetic polymorphism with the onset of diabetic retinopathy and nephropathy; Determination of erythrocyte ALR2 content; Relationship of the protein content of ALR2 in erythrocytes with overt nephropathy.
- Subjects
JAPAN; DIABETIC nephropathies; GENETICS of diabetes; ERYTHROCYTES; ASIANS; DNA; GENETIC polymorphisms; TYPE 2 diabetes; OXIDOREDUCTASES
- Publication
Diabetes, 1999, Vol 48, Issue 2, p420
- ISSN
0012-1797
- Publication type
journal article
- DOI
10.2337/diabetes.48.2.420