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- Title
Endothelial cells play an essential role in the thermal hyperalgesia induced by nerve growth factor.
- Authors
Foster, Paul A.; Costa, Soraia K.P.; Poston, Robin; Hoult, J. Robin S.; Brain, Susan D.
- Abstract
Investigates the mechanisms through which extravasated neutrophils become involved in mediating the thermal hyperalgesia induced by nerve growth factor (NGF). Failure of the hyperalgesia induced NGF to directly activate neutrophils; Manner in which NGF induces neutrophil accumulation in the rat and mouse; Stimulation of neutrophil accumulation and thermal hyperalgesia.
- Subjects
NEUTROPHILS; HYPERALGESIA; PAIN; NERVE growth factor; GROWTH factors
- Publication
FASEB Journal, 2003, Vol 17, Issue 12, p1703
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.02-1000fje