We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Emerging insights in the management of hemoglobin E beta thalassemia.
- Authors
Olivieri, Nancy F.; Thayalsuthan, Vivekanandan; O'Donnell, Angela; Premawardhena, Anuja; Rigobon, Christopher; Muraca, Giulia; Fisher, Christopher; Weatherall, David J.
- Abstract
Globally, hemoglobin (Hb) E β thalassemia accounts for approximately half the severe forms of β thalassemia. Because of its wide clinical diversity and the ability of patients with this condition to adapt unusually well to low hemoglobin levels, the management of Hb E β thalassemia, particularly the decision to instigate regular blood transfusion, is particularly difficult. Here, we present a summary of our work in patients with this condition, which attempts to define clinical, adaptive, and genetic factors of possible value in determining the early management of this condition.
- Subjects
THALASSEMIA; HEMOGLOBINOPATHY; HEMOGLOBINS; BLOOD transfusion; DISEASE management
- Publication
Annals of the New York Academy of Sciences, 2010, Vol 1202, Issue 1, p155
- ISSN
0077-8923
- Publication type
Article
- DOI
10.1111/j.1749-6632.2010.05579.x